摘要
目的了解新疆乌鲁木齐市浅部真菌病发病情况及其病原菌的菌种分布。方法对2004年2月至2010年08月在新疆医科大学第一附属医院皮肤科门诊就诊,临床拟诊为头癣、甲癣、体股癣、手足癣的1 308例患者取病发、皮屑、甲屑行真菌镜检、培养。培养阳性标本在形态学鉴定的基础上行核糖体DNA(rDNA)ITS区序列测定确切鉴定菌种。使用SPSS 17.0统计软件对于结果进行统计分析。结果真菌镜检培养均为阳性患者260例,头癣培养阳性率最高,占33.1%,其次为体股癣占28.8%、甲癣占21.5%、手足癣占16.5%;菌种鉴定:红色毛癣菌为最常见的致病菌(28.5%),其次为须癣毛癣菌(22.3%)、犬小孢子菌(18.8%)、断发毛癣菌(10.0%)。犬小孢子菌为头癣最主要致病菌(16.2%)。统计学分析显示:不同性别、族别间体股癣、手足癣发病率有统计学意义(P<0.05),均好发于男性,汉族发病率高于维吾尔族。不同年龄头癣、甲癣、体股癣、手足癣发病率差异也均有统计学意义(P<0.05),甲癣、体股癣、手足癣好发于中青年,头癣好发于儿童。结论乌鲁木齐市浅部真菌病主要致病真菌是红色毛癣菌。头癣是本地区最主要的儿童浅部真菌病,主要病原菌为犬小孢子菌。
Objective To investigate the etiologic agents of superficial mycosis in Urmuqi and its distribution.Methods Direct microscopic check and fungi cultivation were performed on illness hairs,scales,nail debris of suspected superficial mycosis patients in the Department of Dermatology of the First Affiliated Hospital of Xinjiang Medical University during February 2004 to August 2010.For culture positive samples,bassed on the morphologic identification,the sequences of ITS region of ribosomal DNA（rDNA） were identified.The results were analysed by SPSS 17.0 statistical software.Results There were 260 cases showed positive results in both direct checking and cultivation.The positive rate of Tinea capitis culture was the highest（33.1%）,followed by tinea corporis and cruris（28.8%）,onychomycosis（21.5%）,and tinea manus and tinea pedis（16.5%）.Strain identification revealed that Trichophyton（T.） rubrum was the most common agent in this study（28.5%）,followed by T.mentagrophytes（22.3%）,Microsporun（M.） canis（18.8%） and T.tonsurans（10.0%）.M.canis was the most common causative agent of tinea capitis（16.2%）.Statistical analysis showed that in different genders and nations,tinea corporis and cruris,tinea manus and tinea pedis had statistical difference（P〈0.05）;those disease were all common for men,with the incidence in Han people higher than in Uyghur people.In different ages,tinea capitis,onychomycosis,tinea corporis and cruris,tinea manus and tinea pedis had statistical difference（P〈0.05）.Onychomycosis,tinea corporis and cruris,tinea manus and tinea pedis were common in middle-aged people,while tinea capitis was common in children.Conclusion T.rubrum is the main etiologic agent of superficial mycosis in Urmuqi.Tinea capitis is the most important superficial mycosis for children in this area.M.canis is the most common causative agent of tinea capitis.
出处
《中国微生态学杂志》
CAS
CSCD
2011年第7期637-640,共4页
Chinese Journal of Microecology
基金
国家自然科学基金(30960351)
新疆少数民族科技人才特殊培养计划科研项目(200823113)
新疆维吾尔自治区人力资源与社会保障厅2010年度留学人员科技活动项目择优资助基金
回国人员创业启动基金
关键词
浅部真菌病
致病菌种
红色毛癣菌
犬小孢子菌
Superficial mycoses； Causative agents； Trichophyton rubrum； Microsporum canis；
