摘要
肠道定植有100万亿细菌,这占到了人体细菌总量的绝大多数。一旦肠道菌群失调,就会产生一系列疾病。本文介绍了人体肠道细菌群落异常与5种肠道疾病和5种肠道外疾病的关系,并推荐用益生菌和益生素来治疗人体肠道细菌群落异常。为了解人体肠道细菌群落和人体健康的关系,美国国立卫生研究院已启动了人类微生物组计划,欧洲委员会也正在资助人类肠道宏基因组学项目,而中国在此项目中亦取得了可喜进步。基于肠道宏基因组的个体化医疗时代已不再遥远。
Gut homes 100 trillion microorganisms-the vast majority of our complement of microbes.Shifts in the microbial species that reside in our intestines have been associated with a long list of pathologies.The review introduces a strong correlation between disrupted microbial composition and 5 kinds of gastrointestinal problems as well as 5 kinds of extra-gastrointestinal problems,and recommends probiotics and prebiotics to treat microbiota-associated illness.In order to find out the relationship between human intestinal microbiota and diseases,the National Institutes of Health launched the Human Microbiome Project at the end of 2007,and the European Commission is funding a related effort,called Metagenomics of the Human Intestinal Tract,in which China makes delightful progress.In sum,individual’s therapy based on intestinal metagenomics is coming.
出处
《中国微生态学杂志》
CAS
CSCD
2011年第7期662-666,669,共6页
Chinese Journal of Microecology
关键词
肠道
细菌群落
疾病
宏基因组学
Intestinal； Microbiota； Disease； Metagenomics；
