摘要
目的:评价盐酸米诺环素软膏与氢氧化钙糊剂作为根管消毒剂治疗窦道型根尖周炎的临床疗效。方法:选择75例诊断为窦道型根尖周炎的患者,随机分为3组,每组25例。研究A组和B组分别应用盐酸米诺环素软膏和HY-CALTMMT氢氧化钙糊剂进行根管内封药,对照组采用甲醛甲酚作为根管消毒剂。封药14d复诊时,比较3组患者在封药期间患牙的疼痛情况和临床根尖周指数的变化;在根管充填术完成后6个月,对根管治疗的临床疗效进行评价。结果:研究A组和B组患者在封药期间的疼痛程度显著低于对照组(P<0.05);封药后14d复诊,研究A组和B组患牙的临床根尖周指数显著低于对照组(P<0.05);根管充填术后6个月,研究A组和B组患牙的治疗有效率高于对照组,但无显著差异(P>0.05)。上述3项指标在研究A、B组间均无显著差异。结论:盐酸米诺环素软膏与氢氧化钙糊剂作为根管消毒剂能够有效用于窦道型根尖周炎的治疗。
Objective：To evaluate the effect of minocycline hydrochloride and calcium hydroxide paste on the treatment of refractory and chronic periapical periodontitis.Methods：Seventy five patients with refractory and chronic periapical periodontitis were randomly divided into three groups.The patients in the study Group A and Group B were administered with minocycline hydrochloride or HY-CALTMMT calcium hydroxide paste,respectively.The control group were received formocresol as disinfected agent.The incidences of endondotic interappointment pain were compared among the three groups.The changes of clinical perioapical index（CPI） were analyzed at 14 days after root canal disinfection.The efficacies of root canal therapy were evaluated in 6 months after treatment.Results：The severities of endondotic interappointment pain were significantly lower in both study Group A and Group B than that in the control group（P0.05）.At 14 days after root canal disinfection,there were marked reductions of CPI in study Group A and Group B,both of which decreased significantly compared with that of the control group（P0.05）.The success rates of root canal treatment in the study Group A and Group B were also higher than that in the control group;however,no significant difference could be found（P0.05）.When these three variables were analyzed between study group A and B,no statistical difference were found.Conclusions：Minocycline hydrochloride and calcium hydroxide paste are effective on the treatment of refractory and chronic periapical periodontitis as a root canal disinfected agent.
出处
《中国临床医学》
2011年第3期378-380,共3页
Chinese Journal of Clinical Medicine
关键词
根管治疗
慢性根尖周炎
根管消毒
盐酸米诺环素
氢氧化钙
Root canal therapy
Chronic periapical periodontitis
Root canal disinfection
Minocycline hydrochloride
Calcium hydroxide
