1[1]Hammerschmidt M,Bitgood MJ,McMahon AP.Protein kinase A is a common negative regulator of Hedgehog signaling in the vertebrate embryo.Genes Dev 1996; 10:647-658
2[2]Johnson RL,Scott MP.New players and puzzles in the Hedgehog signaling pathway.Curr Opin Genet Dev 1998; 8:450-156
3[3]Pathi S,Pagan-Westphal S,Baker DP,Garber EA,Rayhorn P,Bumcrot D,Tabin CJ,Blake Pepinsky R,Williams KP.Comparative biological responses to human Sonic,Indian,and Desert hedgehog.Mech Dev 2001; 106:107-117
4[4]Denef N,Neubuser D,Perez L,Cohen SM.Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened.Cell 2000; 102:521-531
5[5]Taipale J,Cooper MK,Maiti T,Beachy PA.Patched acts catalytically to suppress the activity of Smoothened.Nature 2002; 418:892-897
6[6]Chuang PT,McMahon AP.Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein.Nature 1999; 397:617-621
7[7]van den Brink GR,Hardwick JC,Nielsen C,Xu C,ten Kate FJ,Glickman J,van Deventer SJ,Roberts DJ,Peppelenbosch MP.Sonic hedgehog expression correlates with fundic gland differentiation in the adult gastrointestinal tract.Gut 2002; 51:628-633
8[8]Nielsen CM,Williams J,van den Brink GR,Lauwers GY,Roberts DJ.Hh pathway expression in human gut tissues and in inflammatory gut diseases.Lab Invest 2004; 84:1631-1642
9[9]Johnson RL,Rothman AL,Xie J,Goodrich LV,Bare JW,Bonifas JM,Quinn AG,Myers RM,Cox DR,Epstein EH Jr,Scott MP.Human homolog of patched,a candidate gene for the basal cell nevus syndrome.Science 1996; 272:1668-1671
10[10]Hahn H,Wicking C,Zaphiropoulous PG,Gailani MR,Shanley S,Chidambaram A,Vorechovsky I,Holmberg E,Unden AB,Gillies S,Negus K,Smyth I,Pressman C,Leffell DJ,Gerrard B,Goldstein AM,Dean M,Toftgard R,Chenevix-Trench G,Wainwright B,Bale AE.Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome.Cell 1996; 85:841-851