摘要
目的了解华西医院院门诊和住院部2型糖尿病患者中抑郁障碍的患病情况,分析2型糖尿病患者并发抑郁障碍的相关因素,为进一步研究二者的共同病理生理机制提供资料。对象和方法采用横断面研究,收集2009年7月至2010年3月来华西医院就医的2型糖尿病患者共1039例。用自填式问卷的方式调查其社会人口统计学资料、行为因素和疾病情况。统计分析:①描述被调查人群中抑郁障碍的患病率;②用线性回归分析统计抑郁障碍发生的相关因素。结果①2型糖尿病患者中抑郁障碍的患病率:接受调查的2型糖尿病患者中抑郁障碍的患病率为38.3%。住院患者患病率达57.4%,明显高于门诊患者34.6%。②2型糖尿病并发抑郁障碍的相关因素:年龄、MNSI评分、HbA1c等。结论糖尿病患者抑郁障碍的患病率高于正常人群。患者年龄越小、周围神经病变程度越严重、血糖越高,发生抑郁障碍的风险越大。今后可进一步探讨糖尿病患者神经内分泌机制与抑郁障碍之间的关系,为揭示糖尿病患者并发抑郁障碍提供更有力的证据。
Objectives Our study is about to describe the prevalence rate of depressive disorder in type 2 diabetic in- and outpatients of our hospital, and determine the behavioral and clinical characteristics that are associated with depressive disorder. Objects and Methods A cross-sectional study consist of 1039 patients with type2 diabetes from July 2009 to March 2010 in West China Hospital. Demographics, behavioral factors and disease status were collected through self-administered questionnaire.We assessed the degree of diabetic peripheral neuropathy with Michigan neuropathy screening instrument （MNSI）. With these statistics ,we decided to carry out the analysis below： ①We described the prevalence of depressive disorder.②We analyzed the risk factors associated with depressive disorder. Results ①Tbe prevalence of depression among all the type2 diabetes, inpatients, outpatient is 38.3%, 57.4%, 34.6%, respectively. ② The factors associated with depression disorder are： age, HbA 1 c level, scores of MNSI. Conclusion The prevalence rate of depressive disorder among patients with type 2 diabetes is higher than normal population. Patients who are younger, with lower level of HbAlc, and lower degree of peripheral neuropathy are more likely to have depressive disorder. More efforts are needed to find out the relationship between the function of the neuroendocrine system and the depressive disorder.
出处
《中国医药指南》
2011年第20期18-19,共2页
Guide of China Medicine
关键词
2型糖尿病
抑郁障碍
Diabetes mellitus, Type 2
Depressive disorder
