摘要
目的探讨幼儿急疹不同病程外周血白细胞及其分类的变化特点,为其临床诊断提供参考依据。方法收集2002年7月至2010年6月我院急疹留观及住院治疗的532例幼儿急疹病例,对其临床资料、不同病程外周血血象、治疗及预后进行回顾性分析。结果①白细胞总数及中性粒细胞在发热第1天正常或上升,发热第4天白细胞总数及中性粒细胞明显下降,其后血象逐渐上升,病程8d白细胞大多恢复正常,中性粒细胞也较第4天明显上升,病程第14天粒细胞恢复正常。结论①幼儿急疹在病程初期白细胞和中性粒细胞可正常或稍高,高峰期白细胞和中性粒细胞明显下降,恢复期血象基本正常,但中性粒细胞上升时间比白细胞慢。②动态观察外周血象变化有助于幼儿急疹与其他发热性疾病相鉴别。③白细胞及中性粒细胞减少类型与淋巴细胞有很大关系,外周血淋巴细胞比率增高可能是一种保护性的细胞免疫反应。
Objective To investigate the characteristics of WBC count and its assortment in peripheral blood in children who suffered from exanthema subitum at different stage, and to provide data for diagnosis and treatment.Methods From 2002 retrospective study about clinical data, hemogram, treatment and prognosis was done on 532 cases of exanthema subitum. Results The counts of WBC and neutrophilic granulocyte were higher or normal at day 1 of fever,but they were considerably lower at day 4. Levels increased gradually when the patients′ condition improving. The counts of WBC rised to normal level and neutrophilic granulocyte also increased apparently at day 8. Neutrophilic granulocyte rised to normal level at day 14. Conclusion ①In the initial stage of exanthema subitum,an elevated or normal WBC and neutrophilic granulocyte count is usually present. In the acute stage,they decrease apparently,but neutrophilic granulocyte rise slowlier than WBC.②Dynamic viewing hemogram is helpful for differential diagnosis for exanthema subitum and other exanthematous disease.③Decrease type of WBC and neutrophilic granulocyte is relevant to the proportion of lymphocyte. The increase of lymphocyte′s proportionis perhaps a kind of protective cell immunity.
出处
《中国实用医药》
2011年第19期32-33,共2页
China Practical Medicine
关键词
幼儿急疹
中性粒细胞
淋巴细胞
动态变化
Exanthema subitum
Neutrophilic granulocyte
Lymphocyte
Dynamic viewing
