摘要
建立大鼠心肌顿抑模型，观察降钙素基因相关肽（ＣＧＲＰ）对顿抑心肌心功能的影响。发现再灌注前给予ＣＧＲＰ，可显著减轻心肌顿抑的程度，加快缺血后心功能障碍的恢复。
The effects of calcitonin gene related peptide(CGRP) on the cardiac function of stunned myocardium was studied in an in vivo rat model with myocardial stunning. The results suggested that CGRP given intravenously just before reperfusion could significantly lessen myocardial stunning,making a rapid recovery of the postischemic dysfunction. Therefore CGRP could partly prevent the development of myocardial stunning.
基金
军队九五科研基金
关键词
心肌顿抑
基因相关肽
降钙素
心功能
心肌缺血
myocardial stunning gene related peptide,calcitonin cardiac function
