期刊文献+

超高频超声评价糖尿病皮神经损伤的初步研究 被引量:7

Preliminary study of hyperfrequency ultrasound in patients with the diabetic cutaneous nerve neuropathy
原文传递
导出
摘要 目的 探讨超高频超声在2型糖尿病患者腓肠神经损伤中的应用价值.方法 选取有神经症状的糖尿病组、无神经症状糖尿病组和正常对照组的腓肠神经,分别为56条、64条和60条.应用22 MHz超高频超声测量并比较各组神经形态学指标,包括截面积(CSA)、厚/宽比(T/W ratio)以及最粗的神经束厚度(MT)等.结果 ①超声在各组中均可清晰显示腓肠神经的神经外膜、神经束膜和神经束等结构.②对照组、无症状组和症状组的T/W ratio和MT均依次增高,差异具有统计学意义(P<0.05),CSA在三组间差异无统计学意义(P=0.257).结论 超高频超声可显示糖尿病患者的腓肠神经形态学特征,有望为糖尿病皮神经损伤提供一种新的形态学评价工具. Objective To evaluate the morphological changes of sural nerve in patients with type 2 diabetes mellitus by hyperfrequency ultrasound.Methods Fifty-six sural nerves of symptomatic group,64 sural nerves of asymptomatic group,and 60 sural nerves of control group were identified by 22 MHz Ultrasound.The thickness/width (T/W) ratio,cross-sectional areas (CSA) and the maximum thickness of neuronal fascicles (MT) of the sural nerve were calculated in transverse sonograms.Results ①Ultrasound can clearly show these structures of sural nerve such as epineurium,perineurium and nerve bundles and so on.②In symptomatic group,asymptomatic group and control group,T/W ratio and MT were gradually increased,and the differences among the three groups were statistically significant (P〈0.05).Whereas,there were no statistically significant differences in CSA among the three groups (P=0.257).Conclusions22 MHz ultrasound may be a valuable tool in evaluating the diabetic cutaneous nerve neuropathy
出处 《中华超声影像学杂志》 CSCD 北大核心 2011年第7期587-589,共3页 Chinese Journal of Ultrasonography
关键词 超声检查 糖尿病 腓肠神经 Ultrasonography Diabetes mellitus Sural nerve
  • 相关文献

参考文献10

  • 1Greene DA,Stevens MJ, Feldman EL. Diabetic neuropathy:scope of the syndrome. Am J Med,1999,107:2-8.
  • 2Watanabe T, Ito H, Sekine A, et al. Sonographic evaluation of the peripheral nerve in diabetic patients: the relationship between nerve conduction studies, echo intensity, and cross-sectional area. J Ultrasound Med, 2010,29 : 697-708.
  • 3Nishikawa T, Edelstein D, Du XL, et aL Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature, 2000,404 : 787-790.
  • 4Boulton AJ, Malik RA, Arezzo JC, et al. Diabetic somatic neuropathies. Diabetes Care,2004,27 : 1458-1486.
  • 5Vails-Canals J, Povedano M, Montero J, et al. Diabetic polyneuropathy: axonal or demyelinating? Electromyogr Clin Neurorphvsiol. 2002.42,3-6.
  • 6Papanas N,Giassakis G, Papatheodorou K, et ak Sensitivity and specificity of a new indicator test (Neuropad) for the diagnosis of peripheral neuropathy in type 2 diabetes patients: a comparison with clinical examination and nerve conduction study. J Diabetes Complications, 2007,21 : 353-358.
  • 7Lee D,Dauphinee DM. Morphological and functional changes in the diabetic peripheral nerve:using diagnostic ultrasound and neurosensory testing to select candidates for nerve decompression. J Am Podiatr Med Assoc,2005,95:433-437.
  • 8Zhu JA, Li DC, Shao J J, et al. An ultrasound study of anatomic variants of the sural nerve. Muscle Nerve, 2011,43 : 560-562.
  • 9Cartwright MS, Passmore LV, Yoon JS, et al. Cross-sectional area reference values for nerve ultrasonography. Muscle Nerve, 2008,37 : 566-571.
  • 10Quattrini C, Jeziorska M, Malik RA. Small fiber neuropathy in diabetes:clinical consequence and assessment. Int J Low Extrem Wounds,2004,3 : 16-21.

同被引文献40

  • 1姚勇,王任直,张波,柳夫义,魏宇魁.应用周围神经松解术治疗糖尿病性周围神经病[J].中华医学杂志,2005,85(38):2728-2729. 被引量:22
  • 2刘立新,刘好文,王怡洁.美吡哒对2型糖尿病周围神经病变影响的实验研究[J].脑与神经疾病杂志,2005,13(5):366-368. 被引量:1
  • 3管珩,刘志民,李光伟,郭晓蕙,许樟榕,邹大进,邢惠莉,刘伟,盛正妍,田浩明,朱大龙,于德民,庄维特,陈璐璐,翁建平.50岁以上糖尿病人群周围动脉闭塞性疾病相关因素分析[J].中华医学杂志,2007,87(1):23-27. 被引量:119
  • 4Thomas PK. Classification, differential diagnosis, and staging of diabetic peripheral neuropathy. Diabetes, 1997,46 : S54-57.
  • 5Stokvis A, van Neck JW, van Dijke CF, et al. High resolution ultrasonography of the cutaneous nerve branches in the hand and wrist. J Hand Surg Eur Vol,2009,34:766- 771.
  • 6Watanabe T,lto H,Sekine A,et al. Sonographic evaluation of the peripheral nerve in diabetic patients: the relationship between nerve conduction studies, echo intensity, and cross sectional area. J Ultrasound Med, 2010,29 : 697-708.
  • 7Kim WK, Kwon SH, Lee SH, et al. Asymptomatic electrophysiologic carpal tunnel syndrome in diabetics: entrapment or polyneuropathy. Yonsei Med J,2000,41 :123-127.
  • 8Malik RA. The pathology of human diabetic neuropathy. Diabetes, 1997,46 :S50-53.
  • 9Lee D, Dauphinee DM. Morphological and functional changes in the diabetic peripheral nerve: using diagnostic ultrasound and neurosensory testing to select candidates for nerve decompression [J] . J Am Podiatr Med Assoc, 2005, 95: 433-437.
  • 10张大红,刘淑娣,李涛.糖尿病周围神经病变的临床特点及药物治疗[J].中国医药导报,2009,6(10):224-225. 被引量:9

引证文献7

二级引证文献31

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部