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儿童急性髓系白血病的治疗进展

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摘要 儿童急性髓系白血病(AML)是一类造血干细胞的恶性克隆性疾病,其预后与发病年龄、白血病细胞遗传学和化疗的早期反应、是否存在微小残留病(MRD)等密切相关。近年来,AML的细胞遗传学及分子生物学发病机制的研究取得了较大进步,提倡不同危险度分层治疗,儿童AML的治疗效果有了明显改善。本文就儿童AML治疗方案的进展、疗效和预后因素进行综述。
出处 《国际输血及血液学杂志》 CAS 2011年第4期316-320,共5页 International Journal of Blood Transfusion and Hematology
基金 国家自然科学基金(30772367) 广东省自然基金自由申请项目(8151008901000099) 广东省科技计划项目(2008803031066)
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