摘要
目的:探讨32孕周前后胎儿生长受限(FGR)的主要相关因素、脐血流收缩期最大血流速度/舒张期末血流速度的比值(S/D)、终止妊娠的时间、方法以及对围生儿结局的影响。方法:采用回顾性分析方法,收集2009年9月至2010年8月出生的140例FGR患儿母亲的临床资料,将其分为>32孕周组和≤32孕周组,并对两组资料进行分析。结果:≤32孕周组主要相关因素为妊娠期高血压疾病、内科合并症、胎盘因素;>32孕周组主要相关因素为妊娠期高血压疾病、脐带因素。≤32孕周组分娩孕周、新生儿评分、新生儿体重均低于>32孕周组(P<0.05),而围生儿总死亡率、S/D阳性率、早产率高于>32孕周组(P<0.05)。结论:≤32孕周的FGR具有高并发症、合并症和S/D阳性率高的特点,可能是其早产、高围生儿死亡、低新生儿评分、低新生儿体重的重要原因,严重影响围生儿预后;而>32孕周的FGR可能是由于较轻程度的合并症持续作用及晚期脐带因素影响,因其发病孕周较晚,胎儿存活率较高。
Objective： To discuss the correlative factors of fetal growth restriction before and/or after 32-weeks,S/D ratio,delivery time and routine,and fetal outcomes.Methods： 140 cases diagnosed as FGRfrom September 2009 to August 2010 in our hospital were retrospectively reviewed and divided into twogroups： ≤32 weeks group and 32 weeks group.Results： The major correlative factors in ≤32 weeks groupwere gestational hypertension,medical complications,placental factors.The major correlative factors in 32 weeks group were gestational hypertension,umbilical cord factors.Compared with the 32 weeksgroup,the delivery age,neonatal score and birth weight in the ≤32 weeks group were lower（P〈0.05）,but fetal mortality,abnormal S/D positive rate and preterm labor rate were higher（P〈0.05）.Conclusions：FGR before 32 weeks has the characteristics of high complication rate,high abnormal S/D rate,which mightresult in premature labor,high fetal mortality,low neonatal score,low birth weight.FGR happened after 32weeks may be due to relatively minor degree of complications and their continuous efect,and umbilical cordfactors.Because of its late onset in pregnancy,fetal survival rate is high.
出处
《实用妇产科杂志》
CAS
CSCD
北大核心
2011年第7期539-542,共4页
Journal of Practical Obstetrics and Gynecology
关键词
胎儿生长受限
相关因素
分娩
新生儿结局
Fetal growth restriction
Correlative factors
Delivery
Neonatal outcome
