摘要
目的：探讨宫颈癌ⅠB~ⅡB期淋巴结转移的高危险因素以及转移途径,了解盆腔淋巴结的转移规律,为选择性淋巴结切除提供一定的依据。方法：对湖北省荆州市第一人民医院2000年1月~2007年10月的子宫颈癌ⅠB~ⅡB期291例住院手术患者的临床病理资料进行回顾性分析。结果：在291例患者中,盆腔淋巴结转移64例,淋巴结转移率为22.0%。转移部位以闭孔最多,占18.2%（53/291）,其余依次为髂内4.8%（14/291）、髂总3.4%（10/291）、髂外3.1%（9/291）、腹股沟深淋巴结1.7%（5/291）,宫旁淋巴结0.7%（2/291）。淋巴结转移与临床分期、间质浸润深度相关,而患者组织学病理分级、年龄、肿瘤大小、组织学类型与淋巴结转移无关。结论：闭孔淋巴结是子宫颈癌最常见转移部位,可能是宫颈癌的前哨淋巴结。宫颈癌患者的临床分期、间质浸润深度是影响宫颈癌盆腔淋巴结转移的重要因素,而对宫颈癌患者进行手术治疗时应充分考虑这些高危因素。
Objective：To study the risk factors and distribution of retroperitoneal lymph node metastasis in patients with cervical carcinoma in stage IB～ⅡB,so that a basis can be established for determining the site of selective lymph node dissection or sampling.Methods：A total of 291 patients with Stages IB～IIB cervical carcinoma who underwent radical hysterectomy and systematic pelvic lymphadenectomy were investigated from January 2000 to October 2007 in our hospital in Jingzhou city.Results：The overall rate of pelvic lymph-node involvement was 22.0%（64patients）.The obturator lymph nodes were most frequently involved,with a rate of 18.2%（53 of 291 patients）which was followed by the internal iliac（4.8 %;14 of 291 patients）,common iliac（3.4%;10 of 291 patients）,external iliac（3.1%;9 of 291 patients）,deep inguinal nodes（1.7 %;5 of 291 patients）,and parametrial（0.7 %;2 of 291 patients） lymph nodes.Single factor analysis showed that clinical stage and deep cervical stromal infiltration were significantly associated with lymph node metastasis.Age,tumor size,pathologic type,tumor differentiation were not apparently related to metastasis in pelvic lymph nodes.Conclusion：The obturator lymph nodes can be sentinel lymph nodes（SLN） of cervical carcinoma.The influence of metastasis in pelvic lymph node of cervical carcinoma is directly related to the clinical stage,and deep cervical stromal infiltration and operator should consider these risk factors before operations.
出处
《中国妇幼保健》
CAS
北大核心
2011年第20期3070-3072,共3页
Maternal and Child Health Care of China
关键词
子宫颈肿瘤
盆腔淋巴结
转移
回顾性研究
Cervix neoplasm
Pelvic lymph node
Metastasis
Retrospective studies
