摘要
目的探讨2型糖尿病(T2DM)合并非酒精性脂肪肝(NAFLD)的临床特点及危险因素。方法记录两组患者的年龄、性别、身高(H)、体重(W)、血压(BP)、血肌酐(Scr)、血尿酸(UA)等指标,计算体重指数(BMI)=体重(kg)/身高(m2)及腰臀比(WHR)。比较T2DM合并NAFLD(A组,n=69)与T2DM不合并NAFLD(B组,n=75)的患者之间的临床特征。结果两组患者的SBP、DBP、TG无明显差异(P>0.05),A组患者年龄、BMI、FPG、TC、HDL-C、LDL-C、WHR、FINS均高于B组(P<0.05)。BMI、LDL-C、TG是糖尿病脂肪肝形成的主要危险因素(P<0.05)。结论非酒精性脂肪肝是2型糖尿病的主要并发症,是独立于体重指数及脂肪分布类型以外的相关因素。
Objective To investigate the clinical characteristics and related factors of type 2 diabetes mellitus combined with nonalcoholic fatty liver disease （ NAFLD ）. Methods Patients were divided into two groups on the basis of wheather they had NAFLD complications. Age, sex, height （ H ）, weight （ W ）, blood pressure （ BP ）, serum creatinine （ Scr ） and blood uric acid （ UA ） were recorded, and BMI and WHR were calculated in the two groups. Clinical characteristics were compared between T2DM with NAFLD and without NAFLD. Results No significant differences （P 〉 0.05 ） were observed between the two groups on SBP, DBP and TG indexes. But several indexes including age, BMI, FPG, TC, HDL-C, LDL-C, WHR, FINS were remarkably higher than B group. BMI, LDL-C, TG were the main risk factors of fatty liver occurrence in patients with diabetes. Conclusion NAFLD is a major complication and correlative factor independent of body mass index and fat distribution types for patients with type 2 diabetes.
出处
《中国现代医生》
2011年第20期52-53,共2页
China Modern Doctor
关键词
2型糖尿病
非酒精性脂肪肝
胰岛素抵抗
危险因素
Type 2 diabetes mellitus
Nonalcoholic fatty liver disease
Insulin resistance
Risk factors
