摘要
目的应用可吸收线缝合法建立犬双侧髂外动脉狭窄模型。方法全麻下以可吸收线缝合10只大型杂种犬双侧髂外动脉约50%的管腔,术后3个月行血管造影评价动脉狭窄率。结果成功建立8只犬双侧髂外动脉狭窄模型,2只动物死亡。术后3个月的血管造影结果显示管腔狭窄率为(60.6±12.5)%。结论可吸收线缝合法能够建立良好的犬髂外动脉狭窄模型,可为大型动物周围动脉狭窄模型的建立提供参考。
Objective To establish an experimental canine model of bilateral external iliac artery stenosis by surgical method with absorbable suture.Methods Under general anesthesia bilateral external iliac arteries were partly obstructed（about 50%）with absorbable suture in ten dogs.Three months later angiography was performed to evaluate the arterial stricture degree.Results Bilateral external iliac artery stenosis model was successfully established in eight dogs and the other two dogs died within two weeks after the procedure.Angiography performed three months after the procedure showed that the stricture degree of arterial lumen was（60.6 ± 12.5）%.Conclusion Satisfactory experimental canine model of bilateral external iliac artery stenosis can be established by surgical method with absorbable suture.This method can be used for reference when peripheral artery stenosis model is to be prepared in larger animals.
出处
《介入放射学杂志》
CSCD
北大核心
2011年第7期552-554,共3页
Journal of Interventional Radiology
基金
国家自然科学基金(30970811)
高等学校博士学科点专项科研基金(20070159011)
关键词
髂动脉狭窄模型
可吸收线
犬
iliac artery stenosis model
absorbable suture
canine
