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重组人促红细胞生成素治疗肿瘤相关性贫血的研究 被引量:8

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摘要 目的观察重组人促红细胞生成素对肿瘤相关性贫血治疗的疗效。方法将肿瘤相关性贫血患者80例按随机数字表法分为观察组(40例)和对照组(40例),对照组采用常规化疗,观察组在常规化疗基础上加用重组人促红细胞生成素治疗,每次150 U·kg^-1,皮下注射,3次·周^-1,疗程8周;比较2组的疗效。结果观察组在使用重组人促红细胞生成素后第4周和8周,有效率分别为40%(16/40)和70%(28/40);对照组有效率相应为15%(6/40)、25%(10/40)。与对照组治疗后同期比较,观察组有效率较高(均P〈0.05);观察组治疗8周后血红蛋白、红细胞、血细胞比容均高于对照组(均P〈0.05-0.01)。与治疗前比较,观察组治疗后卡氏性能状态评分较高(P〈0.05)。结论应用重组人促红细胞生成素治疗肿瘤相关性贫血疗效明显,能有效提高其血红蛋白水平,改善生活质量。
出处 《实用临床医学(江西)》 CAS 2011年第4期32-33,35,共3页 Practical Clinical Medicine
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