摘要
目的 利用健康仓鼠颊囊粘膜了解两种新型牙科陶瓷材料(Hypress和Hycam)的口腔粘膜刺激作用。方法 61～70天的健康仓鼠30只,分Hypres、Hycam和阴性对照三组各10只,每组试样圆片40片(直径5mm,厚1mm),缝合固定于仓鼠颊囊两侧粘膜上,实验观察两周后作组织切片观察粘膜反应。结果 实验动物均未出现局部及全身的不良刺激反应,组织学观察与阴性对照无显著性差异。结论 两种新型牙科陶瓷材料不具有对口腔粘膜的不良刺激反应。
Objective The aim of the study was to evaluate local and systemic response to two novel dental ceramic mateials (Hypress and Hycam)on hamster's pouch by oral membrane irritation test. Methods The samples of Hypress、Hycam and negative control group (n = 40/group, thickness 1mm, diameter 5mm) were fixed on the oral membrane of hamster's pouch (10/group). After two weeks' local and systemic observation, the local oral membrane specimens were viewed under microscope. Results The results showed that there were no local or systemic abnormal response to the materials and that the histopathological findings were also normal. Conclusion The two new dental ceramic materials have no abnormal oral membrane irritating response.
出处
《口腔材料器械杂志》
1999年第1期26-27,共2页
Chinese Journal of Dental Materials and Devices
关键词
生物相容性
口腔粘膜刺激
牙科材料
牙科陶瓷
Dental porcelain Biocompatibility Oral mucous membrane irritation test
