摘要
目的:探讨使用尿毒清颗粒治疗慢性肾衰竭的临床疗效及应用价值。方法:回顾性分析150例慢性肾衰竭患者,按照入院时间将其先后分为观察组(76例)和对照组(74例)。对照组采用常规饮食和综合治疗,观察组在对照组的治疗基础上加用尿毒清颗粒,每日4次,每次1袋(5.0 g),疗程为2个月。观察和分析两组临床治疗效果、血尿素氮(BUN)及血清肌酐(Scr)的变化情况。结果:治疗2个月后,观察组治疗效果明显优于对照组(P<0.05);观察组BUN、Scr与治疗前相比,明显降低(P<0.05);对照组BUN与治疗前相比明显降低(P<0.05),Scr改变差异无统计学意义(P>0.05);观察组治疗后与对照组相比,BUN、Scr下降差异均有统计学意义(P<0.05)。结论:尿毒清颗粒能明显改善慢性肾衰竭患者的临床症状,延缓肾功能恶化,提高患者的生存质量,费用低且服用方便,值得临床进一步推广应用。
Objective： To investigate the clinical effect and value of Uremic Clearance Granule in the treatment of chronic renal failure. Methods： 150 patients with chronic renal failure patients were divided into observation group （76 cases） and control group （74 cases）. The patients in control group were treated by the conventional diet therapy and comprehensive therapy, and patients in the observation group were taken Uremic Clearance Granule 4 times a day and one bag each time （5.0 g） for 2 months on the basis of the control group. The changes of clinical therapeutic efficacy, blood urea nitrogen （BUN） and serum creatinine （Scr） of two groups were observed and analyzed. Results： The efficacy of two groups were compared after the treatment of 2 months, the observation group was significantly better than those in control group （P〈 0.05）; the BUN, Scr of observation group decreased obviously compare with pretreatment （P〈0.05）; the BUN of control group decreased obviously compare with pretreatment （P〈0.05）, and there was no statistical significance with Scr improve- ment （P〉0.05）; after treatment, the BUN, Scr of observation group had decreased which had statistical significance compare with control group （P〈0.05）. Conclusion： Uremic Clearance Granule has the significant improvement for clinical symptoms of chronic renal failure patients. It could delay the deterioration of renal function and improve the survival quality with cheap and easy administration that it is worthy of clinic application.
出处
《中国医药导报》
CAS
2011年第23期157-158,共2页
China Medical Herald
关键词
慢性肾衰竭
尿毒清颗粒
尿素氮
血清肌酐
Chronic renal failure
Uremic Clearance Granule
Urea nitrogen
Serum creatinine
