摘要
目的对儿童下呼吸道感染病毒进行检测分析,探讨其流行规律。方法 2008年1月-2010年1月,采集毛细支气管炎、支气管肺炎、喘息支气管炎等下呼吸道感染的患儿咽拭子或鼻咽分泌物标本进行常见呼吸道病毒分子生物学检测。结果在701份标本中,病毒阳性382份,阳性率54.5%,感染患儿中呼吸道合胞病毒感染占首位,达29.0%,其次是流感病毒,占22.7%,鼻病毒占14.5%,副流感病毒占12.7%,腺病毒达到8.2%,>2种的病毒混合感染达17.5%。结论儿童下呼吸道感染>50.0%为病毒所致,呼吸道合胞病毒、流感病毒及鼻病毒等是儿童呼吸道感染的主要病原体,混合感染以呼吸道合胞病毒、流感病毒联合其他病毒感染为主,诊治时应根据所感染病原体制定有针对性的措施。
OBJECTIVE To analyze the detected results of pathogen in children with lower respiratory tract infection in order to understand the distribution of the pathogen.METHODS From Jun 2008 to Jun 2010,we detected nasopharyngeal secretion（NPS） from 701 respiratory infection patients.There were RSV,RHV,IV,PIV and ADV in the NPS were detected by multiplex PCR.RESULTS Viruses were detected in 382 patients（54.5%）,Among them,RSV infection was the most frequent,34% of 130 patients.IV was found in 22.7%（102 patients）,RHV in 14.5%（65 patients）,PIV in 12.7%（57 patients）,ADV in 8.2%（37 patients）.CONCLUSION The data indicate that RSV,RHV and IV are important etiological agents for lower respiratory tract infections in children.The manages for diagnosis and treatment depended on the detected results of the pathogen.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第16期3386-3388,共3页
Chinese Journal of Nosocomiology
关键词
呼吸道
病毒
病原体
肺炎
毛细支气管炎
Respiratory tract
Virus
Pathogen
Pneumonia
Broachiolitis
