摘要
目的探讨Ⅰ类手术切口预防性抗菌药物的合理应用。方法观察Ⅰ类手术切口(甲状腺、乳腺、腹外疝)用与不用抗菌药物及术前与术后使用抗菌药物后,患者手术切口发生感染情况。结果所有使用抗菌药物的患者中只有1例患者发生浅部切口红肿的轻度感染症状,感染率为0.3%,患者使用抗菌药物与不使用抗菌药物切口感染率差异无统计学意义;各组手术前后外周血白细胞均差异无统计学意义;Ⅰ类手术切口用与不用抗菌药物,术前、术后体温比较,差异无统计学意义。结论对于Ⅰ类清洁切口不主张应用预防性抗菌药物;当存在可能引起切口感染因素时,若手术时间≤2 h,术前1次使用一代头孢菌素便可达到预防感染的目的 。
OBJECTIVE To investigate the feasibility on rational drug use of antibiotics for type Ⅰ incision during perioperative period.METHODS The cases undergoing elective operations with type Ⅰ operative incision were selected and separated into two groups（prophylactic use of antibiotics or not）.Their infection status were observed and analyzed.RESULTS The incidence of surgical wound infections in two groups had no statistically difference（P0.05）.The body temperature and peripheral blood leucocyte had no statistically difference（P0.05） in each group before and after surgery.CONCLUSIONS It needn′t to prophylactic use of antibiotics for type Ⅰ operative incision.It can accomplish the infection prevention by once use first generation cephalosporin before operation if there is affection and operative time less than 2 hours.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第16期3459-3461,共3页
Chinese Journal of Nosocomiology
关键词
Ⅰ类手术切口
抗菌药物
合理性
药物应用
Type Ⅰ operative incision
Antibiotics
Rationality
Drug utilization
