摘要
目的探讨皮肤黏膜感染病原菌的种类及耐药性,为临床医师合理使用抗菌药物提供科学依据。方法病原菌分离自皮肤黏膜感染患者的脓液或分泌物,病原菌培养鉴定按照《全国临床检验操作规程》进行;药敏试验采用CLSI推荐的K-B法和判读标准。结果皮肤黏膜感染病原菌中分离率居第1位是金黄色葡萄球菌,占25.4%;大肠埃希菌居第2位,占20.1%;铜绿假单胞菌第3位,占16.4%;皮肤黏膜感染病原菌对常用抗菌药物已产生了不同程度的耐药性,但革兰阴性菌对碳青霉烯类、革兰阳性菌对糖肽类抗菌药物敏感率最高。结论应按照细菌培养和药敏试验的结果,合理选用抗菌药物来治疗皮肤黏膜感染。
OBJECTIVE To approach pathogenic species and antimicrobial resistance in skin and mucosa infection to provide the scientific evidence for clinically reasonable use of antibiotics.METHODS Pathogenic bacteria were isolated from liguor puris or secretion from the patients with skin and mucosa infection.Referring to National Guide to Clinical Laboratory Procedures,bacterial culture and identification were performed.The drug susceptibility testing was performed by KB method recommended by CLSI.The susceptibility testing results were assessed.RESULTS The isolating rates of pathogenic bacteria were in the following order of frequency： Staphylococcus aureus（25.4%）,Escherichia coli（20.1%） and Pseudomonas aeruginosa（16.4%）.The susceptibility testing results indicated that varying antimicrobial resistance occurred in pathogenic bacteria against diverse commonly used antibiotics in skin and mucosa infection.The highest susceptibility rates occurred in gram negative bacillus against the carbapenems antibiotics and gram positive coccus against the glycopeptide antibiotics.CONCLUSION The clinician should use the antibiotics to treat skin and mucosa infection according to bacterial culture and susceptibility testing results.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第16期3524-3525,共2页
Chinese Journal of Nosocomiology
关键词
皮肤
黏膜
感染
耐药性
药敏试验
Skin
Mucosa
Infection
Antimicrobial resistance
Susceptibility test
