摘要
目的探讨颈内动脉支架置入血管成形术后脑血流动力学的变化情况。方法对38例颈内动脉中重度狭窄患者行支架置入血管成形术,在手术前后对患者行脑CT灌注成像检查,观察患侧和对侧局部脑血流量(CBF)、脑血容量(CBV)及造影剂平均通过时间(MTT)的变化。结果在支架置入血管成形术前,与对侧比较,患者患侧CBF、CBV降低,MTT延长。与术前比较,患者接受介入手术后患侧CBF、CBV明显增加,MTT明显缩短(P<0.05),与对侧比较,各指标的差异无统计学意义。结论颈内动脉中重度狭窄支架置入血管成形术可使狭窄侧脑血流动力学得到改善。
Objective To evaluate the cerebral hemodynamic changes before and after carotid artery angioplasty and stenting.Methods Thirty-eight patients with moderate/severe internal carotid artery stenosis underwent carotid artery angioplasty and stenting.CT perfusion imaging was performed pre-and post-surgery to determine the cerebral blood flow（CBF）,cerebral blood volume（CBV） and mean transit time（MTT） in the ipsilateral and contralateral cerebrum.Results Before angioplasty and stenting,the CBF and CBV decreased,and MTT increased in the ipsilateral cerebrum than in contralateral cerebrum.After intervention,the CBF and CBV increased and CTT shortened obviously in comparison with that of pre-surgery（P0.05）,while no significant difference was found in comparison with that of contralateral region（P0.05）.Conclusion Angioplasty and stenting may improve the cerebral hemodynamics of patients with severe/moderate internal carotid artery stenosis.
出处
《解放军医学杂志》
CAS
CSCD
北大核心
2011年第8期833-835,共3页
Medical Journal of Chinese People's Liberation Army
关键词
颈动脉狭窄
血管成形术
脑血管循环
carotid stenosis
angioplasty
cerebrovascular circulation
