摘要
目的:通过对不同负荷下兔股骨的压缩性能的对比研究,验证在不同负荷下(电刺激与缺血),兔股骨相同部位表现出的抗载荷能力及对应力松弛反映的影响。方法:制作对照组,电刺激组和结扎缺血模型组的兔股骨标件,分别置于Instron材料力学试验机中进行压缩加载及压缩应力松弛实验。结果:压缩加载实验得出了分别经2周、4周和7周电刺激和缺血训练的兔股骨屈服及断裂的载荷和能量等力学性能指标:对照组模量2697MPa,4周电刺激组模量4051MPa,7周电刺激组模量2818MPa,4周缺血组模量1783MPa,7周缺血组模量1412MPa。压缩应力松弛实验示应力松弛曲线有下降趋势,依次为对照组<7周电刺激组<4周电刺激组<4周缺血组<7周缺血组。结论:短期缺血引起的骨有机质的缺失没有发生质的改变,长期缺血则会使骨质发生严重退变,导致骨脆性增加。适量的电刺激训练可以有效改善这种退变,过量的电刺激则会影响骨内部的基础环境。
Objective： To compare the compression properties of rabbit femur under different loads, to verify the capacity of antagonizing load and the impact of reflecting stress relaxation on the same part of rabbit femur under different loads （electrical stimulation and ischemia）.Method： The standard sample of rabbit femur were made for the control group, the electrical stimulation group and the hgation ischemia model group, and the standard parts were placed in the Instron material-mechanics test-ing machine for compression loading and compression stress relaxation experiments.Result： The compression loading experiments showed the mechanical property indexes as the load and energy of yield and fracture of rabbit femur were obtained after 2 weeks＇, 4 weeks＇ and 7 weeks＇ trainings with electrical stimulation and ischemia： modulus control group was 2697MPa, modulus of electrical stimulation group for 4 weeks and 7 weeks were 4051MPa and 2818MPa respectively, modulus of ischemia group for 4 weeks and 7 weeks were 1783MPa and 1412MPa respectively. The compression stress relaxation experiments showed the corn-presion stress relaxation curves had decline trends and the order of decline trend of stress relaxation were （con-trol group〈7 weeks＇ electrical stimulation group〈4 weeks＇ electrical stimulation group〈4 weeks＇ ischemia group〈7 weeks＇ isehemia group.Conclusion： The loss of bone organic substances caused by short-term ischemia was not a qualitative change, but long-term ischemia would cause serious bone degeneration, increase the bone fragility. Appropriate amount of electrical stimulation could effectively improve bone degeneration, but excessive stimulation would influence the inside basic environment of bone.
出处
《中国康复医学杂志》
CAS
CSCD
北大核心
2011年第8期746-749,共4页
Chinese Journal of Rehabilitation Medicine
基金
江苏省自然科学基金(08KJB180007)
关键词
电刺激
缺血
兔股骨
载荷
应力松弛
electrical stimulation
ischemia
rabbit femur
load, stress relaxation
