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紫杉醇联合奈达铂治疗老年晚期食管癌疗效观察 被引量：9

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摘要 目的观察紫杉醇联合奈达铂治疗老年晚期食管癌的临床疗效和毒副反应。方法紫杉醇135mg/m2静脉滴注d1,奈达铂25mg/m2静脉滴注d2-4,21d为1个周期。结果 26例患者共接受108周期的化疗,所有患者均可评价疗效。其中CR 0例(0%),PR 11例(42.3%),SD 6例(23.1%),PD9例(34.6%),有效率为42.3%,疾病控制率为65.4%。主要毒副反应是骨髓抑制,以Ⅰ～Ⅱ度多见,非血液学毒性较轻。结论紫杉醇联合奈达铂治疗老年晚期食管癌安全,有效,毒副反应可以耐受。
作者 戴秀梅 魏卫 袁保兰
机构地区 江苏省徐州市中心医院肿瘤内科
出处 《齐齐哈尔医学院学报》 2011年第12期1919-1920,共2页 Journal of Qiqihar Medical University
关键词 食管肿瘤 紫杉醇 奈达铂 化疗
分类号 R735.1 [医药卫生—肿瘤]
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参考文献8

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同被引文献68

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齐齐哈尔医学院学报
2011年 第12期

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