摘要
选择60~70 岁老年人和18~25 岁青年人,应用3HTdR掺入法检测淋巴细胞转化能力和血清IL2 水平;用细胞毒活性检测法检测NK细胞活性。结果表明,老年人的上述3 种免疫指标明显低于青年人,说明老年人的细胞免疫功能低下。给老年人服用免疫调节剂4 周后再测定3种指标明显升高,与服免疫调节剂前相比差异显著(P< 0-01),并接近青年人水平。提示免疫调节剂能提高老年人的细胞免疫能力。
The changes of cellular immune function were detected in 60~70 years old healthy subjects comparing to 18~25 years old controls and the effect of immunological modulator on the cellular immune function of elderly subjects was studied.The results showed that the activity of lymphocyte transformation,the level of IL 2 in the blood sera and the activity of PBL NK in the elderly subjects were much lower than those of controls.After treatment of immunological modulator,the above indexes were all enhanced.Thus we believe that immunomodulator can improve the cellular immune function of the old people.
出处
《哈尔滨医科大学学报》
CAS
1999年第6期439-440,共2页
Journal of Harbin Medical University
关键词
免疫调节剂
老年人
细胞免疫功能
immunological modulator
old people
cellular immune function