摘要
肺炎支原体(MP)已成为儿童呼吸道感染的重要病原之一。大量证据表明,MP感染可引起或诱发哮喘的急性发作并导致哮喘慢性症状难以控制。但迄今为止,MP感染诱发或引起哮喘的机制仍不清楚,可能与气道黏膜的损伤、IgE介导的Ⅰ型变态反应及细胞因子和炎症介质的作用有关。文章重点介绍MP感染与哮喘的相关性及其可能的机制。
Mycoplasma pneumoniae（MP）has become one of the important pathogens of childhood respiratory infections.A lot of evidence revealed that MP can cause or induce asthma attack and make the symptoms chronic and uncontrollable.So far,the mechanism remains unclear.Airway mucosal injury,IgE-related type I hyperreactivity,function of cytokines and inflammatory mediators have been suspected to play roles in it.This paper focuses on association of MP infection with asthma and its possible mechanisms
出处
《临床儿科杂志》
CAS
CSCD
北大核心
2011年第8期701-704,共4页
Journal of Clinical Pediatrics
关键词
肺炎支原体
哮喘
儿童
Mycoplasma pneumoniae
asthma
children
