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妊娠高血压综合征超敏C反应蛋白及白蛋白、纤维蛋白原变化分析 被引量:5

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摘要 目的探讨妊娠高血压综合征患者超敏C反应蛋白(hs-CRP)及白蛋白(ALB)、纤维蛋白原(FIB)水平的变化。方法选取住院待产的109例妊娠高血压综合征患者为实验组,其中轻度妊娠高血压综合征患者36例,中度妊娠高血压综合征患者43例,重度妊娠高血压综合征患者30例;选取住院待产的正常孕妇112例为对照组。检测两组hs-CRP及ALB、FIB水平并进行统计学分析。结果实验组的hs-CRP及FIB水平与对照组比较明显升高,差异有统计学意义(P<0.05),且实验组的hs-CRP及FIB水平由轻度到中度再到重度依次升高,差异有统计学意义(P<0.05);实验组中度及重度患者的ALB水平与对照组比较明显下降,差异有统计学意义(P<0.05),且实验组由中度到重度ALB水平依次下降,差异有统计学意义(P<0.05),而实验组轻度患者的ALB水平与对照组比较虽然下降,但是差异无统计学意义(P>0.05)。结论 hs-CRP及ALB、FIB联合检测对妊娠高血压综合征的诊断及病情程度的判断颇有临床意义。
出处 《海南医学》 CAS 2011年第17期115-116,共2页 Hainan Medical Journal
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  • 1褚红女.肝素治疗未足月妊娠羊水过少的疗效评价[J].中华医学杂志,2004,84(9):745-746. 被引量:42
  • 2张通,孟家眉,项曼君.脑卒中后抑郁症的前瞻性研究[J].中华精神科杂志,1996,29(2):73-76. 被引量:174
  • 3刘奕,林明.乳酸脱氢酶作为妊娠期高血压病生化监测指标的临床意义[J].中国全科医学,2006,9(20):1673-1674. 被引量:6
  • 4Ross R. Atherosclerosis - an inflammatory disease [ J ]. N Engl J Med, 1999,340 (2) :115 -126.
  • 5Jialal I, Devaraj S, Inflammation and atherosclerosis: the value of the high - sensitivity C - reactive protein assay as a risk marker[ J]. Am J Clin Pathol, 2001, 116 (Suppl) : 108 - 115.
  • 6Sasaki R, Yamano S, Yamamoto, et al. Vascular remodeling of the carotid artery in patients with untreated essential hypertension increases with age[J]. Hypertens Res, 2002,25:373 -379.
  • 7ThomasL(吕元,朱汉民,沈霞,等译).Clinical Laboratory Diagnostics Use And Assessment of Clinical Laboratory Results [ M ].上海:上海科学技术出版社,2004.677-682.
  • 8Ridker PM, Rifai N, Rose L, et al. Comparison of C - reactive protein and low - density lipoprotein cholesterol levels in the prediction of first cardiovascular events [ J ]. N Engl J Med, 2002,347 : 1557 - 1565.
  • 9Pearson TA, Mensah GA, Alexander RW, et al. Markers of inflammation and cardiovascular disease: Application to clinical and public health practice:A statement for healthcare professionals from the centers for disease control and prevention and American Heart Association [ J]. Circulation,2003,107 (3) :499 - 511.
  • 10Kumru S, Godekmerdan A, Kutlu S, et al. Correlation of maternal serum high - sensitive C - reactive protein levels with biochemical and clinical parameters in preeelampsia[ J]. Eur J Obstet Gyneeol Reprod Biol,2006 Feb 1,124(2) :164 -7.

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  • 1朱明德,石应康.临床医学概要[M].第3版.北京:人民卫生出版社,2009:551-553.
  • 2Lacka K, Czyzyk A. Hormones and the' Cardiovascular sys- tem [J]. Endokrynol Pol,2008,59 (5);420-432.
  • 3Shah TJ, Walsh SW. Activation of NF-kappaB and expres- sion of COX-2 in association with neutrophil infiltration in systemic vascular tissue of women with preeclampsia [ J ]. Am J Obstet Gyneco1,2007,196 ( 1 ) :48. el-48, e8.
  • 4Yamaguchi M ,Ozawa Y, Mishima H, et al. Substance P increases production of proinflammatory eytokines and for- mation of osteoclasts in dental pulp fibroblasts in patients with severe orthodontic root resorption [ J ]. Am J Orthod Dentofacial Orthop ,2008,133 ( 5 ) :690-698.
  • 5O'Connor TM, O'Connell J, O'Brien D!, et al, The role of substance P in inflammatory disease [ J ]. J Cell Physiol, 2004,201 (2) :i67-180.
  • 6Ohshiro H, Suzuki R, Furuno T, et al. Atomic force mi- croscopy to study direct neurite-mast cell (RBL) commu- nication in vitro [ J ]. Immunol Lett, 2001 ,74 ( 3 ) : 211- 214.
  • 7McClellan SA, Zhang Y, Barrett RP,et al. Substance P promotes susceptibility to Pseudomonas aeruginosa kerati- tis in resistant mice: anti-in-flammatory mediators down- regulated [ J ]. Invest Ophthalmol Vis" Sci, 2008,49 ( 4 ) : 1502-1511.
  • 8Creewald L, Becker RC. Expanding the paradigm of the renin-angiotensin system and angiotensin-converting en- zyme inhibitors [ J ]. Am Heart J, 1994,28 ( 5 ) : 997-1009.
  • 9GUO Y H, Hernandez I, Isermann B, et al.Caveolin-l-dependent apoptosis induced by fibrin degradation products[J].Blood, 2009, 113 (18) : 4431-4439.
  • 10Sultan N, Khan M A, Malik S.Effect of folie acid supplementation on hornocysteine level in postmenopausal wornen[J].J Ayub Med Coil Abbottabad, 2007, 19 (4) : 78.

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