摘要
目的:观察应用雷贝拉唑与埃索美拉唑分别治疗十二指肠球部溃疡的临床疗效。方法:将80例十二指肠球部溃疡患者随机分为治疗组和对照组各40例,治疗组给予以埃索美拉唑为主的三联疗法进行治疗,对照组给予以雷贝拉唑为主的三联疗法进行治疗,观察两组临床疗效及Hp根除情况,并进行对比分析。结果:两组总有效率及Hp根除率比较无显著差异(P>0.05);治疗组的临床症状改善情况优于对照组,组间比较有显著差异(P﹤0.05);两组治疗期间未见明显的不良反应发生。结论:以埃索美拉唑为主的三联疗法治疗十二指肠球部溃疡疗效好,Hp根除率高,临床症状改善明显,是一种较佳的治疗方案,值得临床推广应用。
Objective： To observe the clinical effect of rabeprazole and esomeprazole respectively in the treatment of patients with duodenal ulcer.Method： 80 patients with duodenal ulcer were randomly divided into treatment group and the control group,with 40 patients in each group.The treatment group was given the esomeprazole-based triple therapy,the control group was treated with rabeprazole azole-based triple therapy,then observed and analyzed the clinical efficacy and helicobaeter pylori（Hp） eradication.Result： The total effective rate and the rate of Hp eradication had no significant difference between the two groups（P 0.05）;the clinical symptoms of the treatment group was better than that of the control group,there was significant difference between the two groups（P 0.05）;the two groups hadn＇t apparent adverse reactions during treatment.Conclusion： Esomeprazole-based triple therapy is more effective for duodenal ulcer and with higher Hp eradication rate,It can improve clinical symptoms significantly.It is a better treatment,which is worthy of clinical application.
出处
《河北医学》
CAS
2011年第9期1156-1159,共4页
Hebei Medicine
