摘要
目的探讨无创正压机械通气(NPPV)治疗急性胰腺炎并发急性呼吸窘迫综合征(ARDS)的临床价值。方法回顾性分析2007年1月至2010年5月收治的27例急性胰腺炎并发ARDS患者行NPPV治疗的病例资料,对比治疗前后患者心率、呼吸频率、动脉血氧分压(PaO2)、氧合指数(0I)及动脉血二氧化碳分压(PaCO:)的变化情况。结果27例患者中,25例(92.6%)经NPPV治疗后,心率、呼吸频率从上机前的(118.4±13.4)次/min、(32.1±1.7)次/min降低到上机后48h的(81.9±8.5)次/min、(19.9±2.1)次/rain,PaO2、OI及PaC02从上机前的(74.1±5.0)mmHg(1mmHg:0.133kPa)、(148.2±10.0)mmHg、(28.7±1.6)mmHg增加到上机后48h的(110.4±20.8)mmHg、(204.5±71.1)mmHg、(38.4±3.6)mmHg,最终顺利脱机并过渡为文丘里面罩给氧;2例(7.4%)患者呼吸情况恶化,最终改为经口气管插管接有创呼吸机辅助呼吸。结论急性胰腺炎并发ARDS患者使用NPPV治疗的疗效满意。NPPV操作相对简单,容易学习和掌握,并发症少,值得在临床上推广应用。
Objective To evaluate the clinical value of noninvasive positive-pressure ventilation (NPPV) treatment in acute respiratory distress syndrome caused by acute pancreatitis. Methods A retrospective study of 27 cases, with acute respiratory distress syndrome (ARDS) caused by acute panereatitis, who were admitted to our department from Jan 2007 to May 2010 and treated with NPPV, was performed. The changes of heart rate, respiratory rate, Pa02, oxygenation index (0I) and PaCO2 before and after treatment were compared. Results The heart rate, respiratory rate of 25 (92.6%) patients decreased from ( 118.4 ± 13.4)/min, (32.1±l.7)/min to (81.9±8.5)/rain, (19.9 ±2.1)/min; PaOz, OI and PaCO2 increased from (74.1 +5.0)mmHg, (148.2±10.0)mmHg, (28.7 +l.6)mmHg to (110.4 +20.8)mmHg, (204.5 ± 71.1 ) mmHg, (38.4 ± 3.6) nunHg 48 h after NPPV, respectively, and they recovered and were transited to oxygen supply by Venturi mask. 2 (7.4%) patients deteriorated and were transited to invasive positive-pressure ventilation support. Conclusions NPPV could effectively improve oxygenation of patients with ARDS caused by acute pancreatitis. The procedure of NPPV is relatively easy to use and to learn with few complications, and worth of clinical application.
出处
《中华胰腺病杂志》
CAS
2011年第4期237-239,共3页
Chinese Journal of Pancreatology
关键词
胰腺炎
呼吸窘迫综合征
成人
回顾性研究
无创正压机械通气
Pancreatitis
Respiratory distress syndrome, adult
Retrospective studies
Noninvasive positive-pressure ventilation