摘要
目的分析食管胃结合部腺癌（AEG）的淋巴结转移规律，为其手术范围提供参考依据。方法选择我院1989年1月至2010年12月行根治性切除手术的食管胃结合部腺癌119例，记录每例患者的淋巴结数目和大小，计算淋巴结总数和平均值，计算总体淋巴结转移率以及分组淋巴结转移率。结果119例手术标本共检出淋巴结6537枚（30～157枚），平均（54．93±19．20）枚／例。119例中89例有淋巴结转移，总体淋巴结转移率74．79％，SiewertⅠ、Ⅱ和Ⅲ型患者的淋巴结转移率分别为47．62％、71．11％和88．68％（χ2=13．968，P〈0．01）。SiewertI型患者有N0．1～4、N0．19—20和No．110～112淋巴结转移，No．5～6和N0．10—11淋巴结无转移；不同的是，SiewertⅡ型和Ⅲ型患者有No．5～6和No．10～11淋巴结转移，而No．111～112淋巴结无转移。结论食管胃结合部腺癌的淋巴结转移有明显规律，有助于指导手术范围。
Objective To investigate the regularity of lymph node metastasis in adenocarcinomas of the esophagogastric junction in order to guide the extent of resection. Methods The clinicopathological data of 119 patients with adenocarcinomas of the esophagogastric junction who underwent radical surgery in our hospital from January 1989 to December 2010 were retrospectively analyzed. The number and size of detected lymph nodes were recorded. The sum and the average number of detected lymph nodes, and the total and sectionalized ratio of lymph node metastasis were calculated. Results A total of 6537 （ 30-157 ） lymph nodes were detected from the surgical specimens of 119 patients with adenocarcinomas of the esopha- gogastric junction, and the average number of detected lymph nodes was 54. 93～ 19. 20. The total ratio of lymph node metastasis was 74.79% （89/119）. The metastasis rate in patients with Siewert types Ⅰ, Ⅱ and Ⅲ was 47. 62%, 71.11% and 88. 68% （χ2 = 13. 968, P 〈 0. 01 ） respectively. The involved lymph nodes were located at No. 1-4, No. 19-20 and No. 110-112 in patients with Siewert type I, but no metas- tasis was found in No. 5-6 and No. 10-11 lymph nodes. In contrast, metastasis was found in No. 5-6 and No. 10-11 lymph nodes, but not in No. 111-112 lymph nodes in patients with Siewert types Ⅱ and Ⅲ. Conclusion The metastasis of lymph nodes in adenocarcinomas of the esophagogastric junction has certain regularity, which can provide a significant guidance for the extent of resection.
出处
《中华实验外科杂志》
CAS
CSCD
北大核心
2011年第9期1574-1576,共3页
Chinese Journal of Experimental Surgery
关键词
食管胃结合部腺癌
转移
淋巴结切除术
胃切除术
脾切除术
Adenocarcinomas of the esophagogastric junction
Metastasis
Lymphadenecto- my
Gastrectomy
Spleneetomy
