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早期乳腺癌新辅助化疗联合保乳术治疗的临床效果分析 被引量:30

Neoadjuvant chemotherapy in early breast cancer breast-conserving surgery for analysis of clinical effects
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摘要 目的:探讨环磷酰胺(CTX)+吡柔比星(THP)+氟尿嘧啶(FU)方案新辅助化疗后行乳腔镜保乳手术疗效及美容效果。方法:对2006年9月~2010年9月在本院行新辅助化疗联合保乳术治疗的30例早期乳腺癌患者的临床资料进行回顾性分析。结果:30例患者经治疗后客观有效率RR为93.3%,所有患者均存活,术后患者患侧乳房满意度好以上达到96.7%,部分患者出现不同程度骨髓抑制恶心、呕吐、脱发等不良反应,经处理后均可较好耐受。结论:早期乳腺癌采取新辅助化疗联合保乳术治疗,疗效显著,便于保乳并且美容效果好。 Objective:To investigate the cyclophosphamide (CTX) + pirarubicin (THP) + fluorouracil (FU) neoadjuvant chemotherapy underwent endoscopic breast conserving surgery and cosmetic results.Methods:From September 2006 to September 2010 in our hospital neoadjuvant chemotherapy and breast-conserving surgery for early breast cancer patients 30 patients were retrospectively analyzed.Results:30 patients with objective response rate after treatment RR was 93.3%,all patients were alive after a good patient satisfaction more than ipsilateral breast 96.7%,in some patients with varying degrees of bone marrow suppression,nausea,vomiting,hair loss and other adverse reactions,after treatment may be better tolerated.Conclusion:Early breast cancer to neoadjuvant chemotherapy and breast-conserving treatment,a significant effect,easy and cosmetic results of breast-conserving good.
作者 陈基善
出处 《中国当代医药》 2011年第10期30-31,共2页 China Modern Medicine
关键词 早期乳腺癌 新辅助化疗 保乳术 临床效果 With early breast cancer Neoadjuvant chemotherapy Conserving surgery Clinical effect
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  • 1骆成玉,薛镭,林华,黄旋,杨齐,李国华,张键,张勇智.乳腔镜微小隐蔽切口切除乳腺良性肿块的临床观察[J].中华医学杂志,2003,83(14):1233-1235. 被引量:54
  • 2刘阳,王立国.保乳手术治疗早期乳腺癌的临床分析[J].实用医学杂志,2006,22(20):2411-2412. 被引量:28
  • 3Veronesi U, Cascinelli N, Mariani L, et al. Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer [J]. N Engl J Med, 2002, 347(16) : 1227-1232.
  • 4Fisher B, Anderson S, Bryant J, et al. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of breast cancer [J ]. N Engl J Med, 2002, 347(16) : 1233-1241.
  • 5Amanti C, Regolo L, Moscaroli A, et al. Total periareolar approach in breast con-serving surgery [ J ]. Tumori, 2003, 89 (4 Suppl) : 169-172.
  • 6Petit J Y, Garusi C. One hundred and eleven cases of breast conservation treatment with simultaneous reconstruction at the European Institute of Oncology (Milan) [J]. Tumori, 2002, 88 ( 1 ) :41-47.
  • 7Jones SE,Savin MA,Holmes FA,et al.Aduvant Phase Ⅲ trial comparing doxorubicin plus cyclophosphamide with docetaxel plus cyelophosphamide as adjuvant therapy for operable breast eaneer[J].Clin Oncol,2006,24:5381-7.
  • 8Buehholz TA,Hunt KK,W hitman GJ.et al.Neoaduvant chem-otherapy for breast carcinoma:muhidiscip linary considerations of benefits and risks[J].Cancer,2003,15,(6):1150-1160.
  • 9林本耀.乳腺癌[M].第1版.北京:中国医药科技出版社,2006:263-264.
  • 10De Wilde RL,Schmidt EH,Hesseling M,et al.Comparison of classic and endoscopeic lymphadenectomy for staging breast cancer[J].J Am A SSOC Gynecol Laparosc.2003,10(1):75-79.

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