摘要
肠黏膜不仅担负着消化吸收、机体与外界进行物质交流的重要生理功能．而且是人体最大的免疫器官与黏膜屏障（肠屏障）。这一屏障的损害与许多疾病、尤其是术后并发症相关。食管癌围手术期的许多因素影响着肠屏障功能的完整．其中以低灌注与禁食水的损害最甚。了解肠屏障包括其机械、生物与免疫屏障的机制．了解益生菌的重要生理功能及早期肠内营养对肠屏障的保护作用．是食管癌手术快速康复的重要组成部分。
Intestinal mucosa plays important roles in digestion, absorption and substance exchange between organism and external environment. Meanwhile, it is the largest immune organ and mucosal harrier, including mechanical, biological and immune barrier. A variety of diseases, especially postoperative complications, are associated with the damage of mucosal barrier. Esophageal cancer surgery is complex and many perioperative factors, especially hypoperfusion and fasting, may affect the integrity of intestinal barrier. Understanding of the mechanism of intestinal barrier （mechanical, biological and immune barrier）, the physiological function of probiotics, and the benefit of early enteral nutrition to intestinal barrier are important components to acheive fast recovery after surgery for esophageal cancer.
出处
《中华胃肠外科杂志》
CAS
北大核心
2011年第9期671-673,共3页
Chinese Journal of Gastrointestinal Surgery
关键词
食管肿瘤
围手术期
肠屏障
Esophageal neoplasms
Pefioperative
Intestinal mucosa barrier
