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Megsin与肾脏疾病

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摘要 肾小球系膜细胞(glomerular mesangial cell,GMC)是肾脏重要的固有细胞之一,维持着肾脏的组织结构和生理功能,具有产生细胞外基质(extracellular matrix,ECM)、分泌细胞因子(cytokine,CK)、吞噬和清除异物等多种功能,同时也参与了肾小球疾病尤其是系膜增生性疾病的发生、发展。Megsin是近10年来被新认识的GMC优势表达基因,本文就megsin与肾脏疾病的关系做一综述。
出处 《临床肾脏病杂志》 2011年第8期377-379,共3页 Journal Of Clinical Nephrology
基金 河北省自然科学基金项目(C2010000583) 河北省卫生厅重大项目(20090008)
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