摘要
目的探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者的体重指数(BMI)与白天嗜睡及呼吸功能紊乱的关系。方法经多导睡眠图(PSG)确诊为OSAHS的患者114例,按BMI<24kg/m2(正常)、24kg/m2≤BMI<28kg/m2(超重)及BMI≥28kg/m2(肥胖)分为3组。采用Epworth嗜睡量表(ESS)及多导睡眠图测量其白天嗜睡状况及呼吸功能指标(如:呼吸暂停低通气指数(AHI)、夜间平均氧饱和度(MSaO2)、最低氧饱和度(LSaO2)、氧饱和度<90%时间占睡眠时间的百分比(Sa90))。结果肥胖组的ESS、AHI、Sa90均显著高于超重组和正常组,而MSaO2、LSaO2显著低于这两组(P<0.05)。相关分析结果显示:BMI与ESS、AHI、Sa90呈显著正相关(P<0.01),与MSaO2、LSaO2呈显著负相关(P<0.01)。结论肥胖对OSAHS患者的白天嗜睡症状及呼吸功能均有影响。
Objective：To explore the relationship between daytime sleepiness ,respiratory dysfunction and body mass index （BMI） in patients with obstructive sleep apnea hypopnea syndrome（OSAHS）. Methods： 114 patients with OSAHS were diagnosed by polysomnogram（PSG） and grouped according to BMI. The status of sleepiness were tested by the Epworth Sleepiness Scale （ESS）. The.respiratoIy parameters （ such as apnea hypopnea index （AHI） ,mean Oxygen Saturation （MSaO2 ） , Lowest Oxygen Saturation （LSaO2 ） , the percent of the total time with oxygen saturation level 〈 90% （Sa90）were tested by PSG）. Results：Tile mean global score of ESS, AHI and Sa90 are significantly higher in obeses group than the overweigth and normal group. The MSaO2 , LSaO2 are significantly lower in obeses group than the overweight and normal group（P 〈 0.05 ）. There were significantly correlation between ESS, AHI, MSaO2, LSaO2 ,Sa90 and BMI （P 〈 0.01 ）. Conclusion：BMI may affect the daytime sleepiness, respiratory function and arterial oxygen saturation in patients with OSAHS.
关键词
阻塞性睡眠呼吸暂停综合征
体重指数
嗜睡
呼吸功能
Obstructive sleep apnea hypopnea syndrome
Body mass index
Sleepiness
Breathing disfunction
