摘要
目的:观察母系印迹基因p57KIP-2在水泡状胎块组织中蛋白的表达情况,探讨检测p57KIP-2蛋白对鉴别不同类型水泡状胎块组织的意义。方法:用免疫组化方法检测p57KIP-2蛋白在23例部分性水泡状胎块中的表达情况。结果:23例部分性水泡状胎块p57KIP-218例表达阳性。结论:p57KIP-2蛋白在水泡状胎块组织中的表达与其临床分型有关,检测p57KIP-2对鉴别不同类型的水泡状胎块有临床意义。
Purpose：To detect the protein expression of p57^KIP - 2 in the hydatidiform mole tissue, and to explore its significance in discrimination of the two subtypes of hydatidiform mole. Methods：p57^KIP - 2 expression in 23 partial hydatidiform mole were detected by immunohistochemiscal method. Results： There were 18 cases expression of p57^KIP - 2 in 23 cases of partial hydatidiform mole. Conclusions ： The expression of p57^KIP - 2 in hydatidiform mole is significantly associated with clinical stage, and p57^KIP - 2 immunohistochemical analysis in addition to routine pathologic evaluation could greatly facilitate the differential diagnosis of hydatidiform mole.
