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Docetaxel-induced nail toxicity： a case of severe onycholysis and topic review 被引量：1

Docetaxel-induced nail toxicity： a case of severe onycholysis and topic review
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摘要 Docetaxel is a commonly-used anti-cancer chemotherapeutic agent given its efficacy in a large variety of solid tumors. It is associated with various adverse effects one of which is nail toxicity. We report a case of severe onycholysis as a result of treatment with docetaxel in a patient who suffered from metastatic nasopharyngeal carcinoma. The case report will be followed by a discussion on the possible mechanism and preventive strategies for taxane-induced nail toxicity. Docetaxel is a commonly-used anti-cancer chemotherapeutic agent given its efficacy in a large variety of solid tumors. It is associated with various adverse effects one of which is nail toxicity. We report a case of severe onycholysis as a result of treatment with docetaxel in a patient who suffered from metastatic nasopharyngeal carcinoma. The case report will be followed by a discussion on the possible mechanism and preventive strategies for taxane-induced nail toxicity.
作者 Chi-pan Lau Pun Hui Tak-cheung Chan
机构地区 Department of Clinical Oncology State Key Laboratory inOncology in South China Sir Y. K. Pao Centre for Cancer
出处 《Chinese Medical Journal》 SCIE CAS CSCD 2011年第16期2559-2560,共2页 中华医学杂志（英文版）
关键词 DOCETAXEL onycholysis nail toxicity Docetaxel onycholysis nail toxicity
分类号 TQ463.5 [化学工程—制药化工] TS974.1 [轻工技术与工程]
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参考文献9

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Chinese Medical Journal
2011年 第16期

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