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近日节律在肿瘤治疗中的应用进展 被引量：3

Applications in advances of circadian rhythm in cancer treatment
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摘要 近日节律是生物生命活动的基本特征之一,它与肿瘤的发生、发展、转移和预后紧密相关,并影响抗癌药物的耐受性和疗效。研究近日节律与肿瘤的相关性,利于预防、诊断和治疗恶性肿瘤,提高患者存活率和生活质量。本研究就近日节律在肿瘤治疗中的应用作一综述,以期为近日节律的进一步研究奠定基础。 Circadian rhythm was one of the basic features of life activities.Further more,it was crucial to the occurrence、 development、metastasis and prognosis of cancer.The circadian clock was also responsible for predictable changes in the tolerability and efficiency of anticancer agents.Therefore,more research on relationship between circadian rhythm and cancer can help us to do better in prevention、diagnosis and treatment of cancer,as well as improve survival and quality of patients.
作者 钟银杭 王立强 许瑞安 刁勇
机构地区 华侨大学分子药物研究所
出处 《中国医药科学》 2011年第17期34-36,共3页 China Medicine And Pharmacy
关键词 近日节律 肿瘤 时辰治疗学 时辰药理学 时辰化疗 Circadian rhythm Cancer Chronotherapy Chronopharmacology Chronochemotherapy
分类号 R96 [医药卫生—药理学]
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参考文献27

  • 1朱莉.常规化疗与时辰化疗在晚期结直肠癌治疗中的临床观察[J].江西医药,2010,45(5):455-457. 被引量：4
  • 2D. R. Penberthy,T. A. Rich,C. H. Shelton,R. Adams,J. S. Minasi,R. S. Jones.A pilot study of chronomodulated infusional 5-fluorouracil chemoradiation for pancreatic cancer[J]. Annals of Oncology . 2001 (5)
  • 3Shigehiro OHDO.Chronopharmaceutics:pharmaceutics focused on biological rhythm. Biological and Pharmaceutical Bulletin . 2010
  • 4Kang TH,Sancar A.Circadian regulation of DNA excision repair implications for chrono-chemotherapy. Cell Cycle . 2009
  • 5Levi F,Focan C,Karaboue A,et al.Implications of circadian clocks for the rhythmic delivery of cancer therapeutics. Advanced Drug Delivery Reviews . 2007
  • 6Hrushesky WJM,Grutsch J,Wood P,et al.Circadian clock manipulation for cancer prevention and control and the relief of cancer symptoms. Integr Cancer Ther . 2009
  • 7N. Asnaa b H. Lewya I.E. Ashkenazia V. Deutschc H. Peretzd M. Inbarb a.Time dependent protection of amifostine from renal and hematopoietic cisplatin induced toxicity. Life Sciences . 2005
  • 8Abolmaali K,Balakrishnan A,Stearns AT,et al.Circadianvariation in intestinal dihydropyrimidine dehydrogenase(DPD)expression:a potential mechanism for benefits of 5FU chrono-chemotherapy. Journal of Surgery . 2009
  • 9Zeng Z L,Sun J,Guo L,et al.Circadian rhythm in dihydropyrimidine dehydrogenase activity and reduced glutathione content in peripheral blood of nasopharyngeal carcinoma patients. Chronobiology International . 2005
  • 10Levi F.The circadian-timing system:A determinant of drug activity and a target of anticancer treatments. Annales Pharmaceutiques Francaises . 2008

二级参考文献9

  • 1Petit E,Milano G,Levi F et al.Cireadian rhythm-varying plasma concentration of 5-fluorouraeil during a 5-day continuous venous infusion at a constant rate in cancer patients.Cancer Res,1998,48(6):1676.
  • 2Harris BE,Song R,SoongSJ,et al.Relationship between in dihydropyrimidine dehydrogenase aetivity and plasmas5-fluorouraeil levels with evidence for circadian variation of enzyme activity and plasma drug levels in cancer patients receiving 5-fluorouracil by protraeted continuous infusion.Cancer Res,1990,50(l):197.
  • 3Falconen A,Allegrini G,Antonuzzo A,el al.Infusions of Fluorouracil and Leucovorin:Effects of Timing and Semi-intermittency of drug delivey.Oncology,1999,57(3):195.
  • 4Cvitkovic E.A historical perspective on oxaliplatin:rethinking the role of platinum compounds and learning from mear misses.Semin Oncol,1998,25 (2):1.
  • 5Meister A,Selective modification of glutathione metabolism.Science,1983,220(4596):472.
  • 6Levi F.Chronopharmacology of anticancer agents.In:Redfern PH,Lemmer B,eds.Physiology and pharmacology of biological rhythm.Berlin:Springer-Verlag.1997.299.
  • 7Boughattas NA,Levi F,Fournier C,et al.Stable circadian mechanisms of toxicity of two platinum analogs (cisplatin and carboplatin) despite repeated dosages in mice.J Pharmacol Exp Ther,1990,255(2):672.
  • 8Levi F,Metzger G,Massari G,et al.Oxaliplatin:pharmacokinetics and chronopharmacolog -ical aspects.Glin Pharmacokinet,2000,38(1):1.
  • 9Granda TG,Levi F.Tumor-based rhythms of anticancer efficacy in experimental models.Chronobiol Int.2002 ;19(1):21.

共引文献3

同被引文献37

  • 1王秀荣,王建华,云晓蕊,沈丹薇.胃癌与直肠癌时辰化疗的护理[J].中国实用护理杂志（下旬版）,2006,22(11):45-45. 被引量：9
  • 2[2]陈振东,孙燕,王肇炎.实用肿瘤并发症诊断治疗学[M].合肥:安徽科学技术出版社,1998.421～ 456.
  • 3周均田,邬麟,徐建华,胡炳强,殷先利,李旭英,曾毅栋,林荷梅,刘振洋.NP方案时辰化疗治疗非小细胞肺癌的临床研究[J].临床肿瘤学杂志,2007,12(8):583-586. 被引量：12
  • 4Bernard S, Bernard BC, Levi F, et al. Tumor growth rate determines the timing of optimal chronomodulated treatment schedules. Plos Computationalbiology,2010,6 (3) : e100-e112.
  • 5Levi F, Okyar A. Circadian clocks and drug delivery systems: impact and opportunities in chrcnotherapeutics. Expert Opin Drug Deliv,2011,8 (12) : 1535-1541.
  • 6Hatake K. Risk management in ambulatory anti-cancer therapy, focusing on nausea and vomiting. Gan To Kagaku Ryoho,2011, 38( 11 ) :1758-1760.
  • 7Vidall C, Dielenseger P, Farrell C, et al. Evidence-based management of chemotherapy-induced nausea and vomiting: a position statement from a European cancer nursing forum. E cancer medicalscience ,2011,28 (5) :211-216.
  • 8Secq M. Chronotherapy in oncology , Nursing care, The private duty nurse facing ehronotherapy, Interview by Isabelle Levy. Soins,2008,25 (6) :21-24.
  • 9Kearney N, Miller M, Maguire R, et al. WISECARE + : Results of a European study of a nursing intervention for the management ofchemotherapy-related symptoms. Eur J Oncol Nurs, 2008, 12 (5) :443-448.
  • 10Levi F. The circadian-timing system: A determinant of drug activity and a target of anticancer treatments. Ann Pharm Fr, 2008,66(3) :175-184.

引证文献3

二级引证文献15

中国医药科学
2011年 第17期

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