摘要
目的:研究保济丸对胃肠运动功能的作用。方法:通过观察保济丸(0.15,0.3,0.6 g.kg-1)对正常小鼠小肠推进功能、对肠肌运动亢进小鼠的小肠运动、对正常小鼠胃排空、对阿托品致胃肠运动功能低下小鼠胃排空的影响来评价来评价保济丸对胃肠功能的作用。结果:保济丸能明显抑制小鼠胃排空,增加胃中酚红的残留率;抑制正常小鼠及肠功能亢进小鼠的小肠推进作用,明显抑制推进距离和推进率。结论:保济丸具有解痉作用。
Objective：To study the effects of Baoji Wan on gastrointestinal motility.Method：Impacts of Baoji Wan on gastrointestinal motility were evaluated through observing the small intestine function in normal mice,the intestinal movement of mice with hyperactive muscle movemen in small intestinet,gastric emptying in normal mice,the lower gastric emptying gastrointestinal motility induced by atropine.Result：Baoji Wan could significantly inhibit gastric emptying and increase the retention rate of phenol red in stomach;suppress normal mice and mice with hyperthyroidism intestine of small intestine function,significantly inhibit the rate of advance and promote distance.Conclusion：Baoji Wan have antispasmodic effects,which provide an experimental basis for clinical application.
出处
《中国实验方剂学杂志》
CAS
北大核心
2011年第18期229-231,共3页
Chinese Journal of Experimental Traditional Medical Formulae
关键词
保济丸
胃肠运动
阿托品
Baoji Wan
gastrointestinal motility
atropine
