摘要
目的研究延龄草Trillium tschonoskii根及根茎中的化学成分。方法采用硅胶、聚酰胺、反相硅胶C18和Sephadex LH-20柱色谱对延龄草70%乙醇提取物进行了分离纯化。用质谱、一维及二维核磁等波谱学方法确定了化合物结构。结果从延龄草醋酸乙酯和正丁醇部位分离鉴定得到8个化合物,分别鉴定为偏诺皂苷元-3-O-α-L-吡喃鼠李糖基-(1→2)-β-D-葡萄糖苷(1)、偏诺皂苷元-3-O-α-L-吡喃鼠李糖基-(1→4)-[α-L-吡喃鼠李糖基-(1→2)]-β-D-葡萄糖苷(2)、偏诺皂苷元-3-O-α-L-吡喃鼠李糖基-(1→4)-α-L-吡喃鼠李糖基-(1→4)-[α-L-吡喃鼠李糖基-(1→2)]-β-D-葡萄糖苷(3)、偏诺皂苷元(4)、薯蓣皂苷元(5)、7,11-dimethyl-3-methylene-1,6-dodecadien-10,11-dihdroxyl-10-O-β-D-glucopyranosyl-(1→4)-O-β-D-glucopyranoside(6)、7,11-dimethyl-3-methylene-1,6-dodecadien-10,11-dihdroxyl-10-O-β-D-glucopyranoside(7)、紫云英苷(8)。结论所有化合物均为首次从该种植物中分离得到。
Objective To investigate the chemical constituents in the roots and rhizomes of Trillium tschonoskii.Methods The roots and rhizomes of T.tschonoskii were extracted with 70% ethanol and separated by polyamide,silica gel,RP-C18,and Sephadex LH-20 column chromatography.Chemical structures were identified by MS,1D and 2D NMR spectroscopy.Results Eight compounds were isolated and their structure were identified as pennogenin-3-O-α-L-rhamnopyranosyl-（1→2）-β-D-glucopyranoside（1）,pennogenin-3-O-α-L-rhamno-pyranosyl-（1→4）-[α-L-rhamnopyranosyl-（1→2）]-β-D-glucopyranoside（2）,pennogenin-3-O-α-L-rhamnopyranosyl-（1→4）-α-L-rhamnopyranosyl-（1→4）-[α-L-rhamnopyranosyl-（1→2）]-β-D-glucopyranoside（3）,pennogenin（4）,prosapogenin（5）,7,11-dimethyl-3-methylene-1,6-dodecadien-10,11-dihdroxyl-10-O-β-D-glucopyranosyl-（1→4）-O-β-D-glucopyranoside（6）,7,11-dimethyl-3-methylene-1,6-dodecadien-10,11-dihdroxyl-10-O-β-D-glucopyranoside（7）,and astragalin（8）.Conclusion All these compounds are isolated from T.tschonoskii for the first time.
出处
《中草药》
CAS
CSCD
北大核心
2011年第9期1689-1691,共3页
Chinese Traditional and Herbal Drugs
基金
江西教育厅青年基金资助项目(GJJ10210)
"产学研结合培养高素质复合型中药人才模式创新研究与实践"项目(教高函[2007]29号)
关键词
延龄草
偏诺皂苷
倍半萜苷
薯蓣皂苷元
紫云英苷
Trillium tschonoskii Maxim.
pennogenin
sesquiterpene glycoside
prosapogenin
astragalin
