摘要
目的:评价艾司西酞普兰治疗抑郁症的临床疗效及安全性。方法:用艾司西酞普兰和氯米帕明对66例住院抑郁症患者进行为期6周的随机对照研究。应用HAMD、CGI-SI及TESS量表评估和比较两者的疗效及安全性。结果:治疗6周后,艾司西酞普兰组和氯米帕明组的有效率分别为87.50%和84.38%,两组患者疗效差异无显著性(P>0.05);艾司西酞普兰不良反应明显少于氯米帕明(P<0.01),且耐受性好。结论:艾司西酞普兰治疗抑郁症疗效好,安全性高。
Objective：To evaluate the efficacy and safety of escitalopram in treatment of depression. Methods：66 inpatients with depression were randomly assigned to receive escitalopram and elomipramine for 6 weeks. All the inpatients were evaluated with HAMD ,CGI - SI and TESS. Antidepressive effective was compared between 2 drugs. Results： At 6 weeks ,the effective rate of escita lopram group and the elomipramine group were 87.50% and 84.38% respectively, there was no significant difference in clinical efficacy between the two groups （ P 〉 0.05 ） ; Escitalopram showed significantly less side effects than did clomipramine （ P 〈 0.01 ） and good drug tolerability. Conclusions ： Escitalopram has been proved to be effective and safe in the treatment of patients with depression.
出处
《中国民康医学》
2011年第17期2136-2137,共2页
Medical Journal of Chinese People’s Health
