期刊文献+

早期乳腺癌保留乳房治疗18年疗效观察 被引量:4

A 18-year Follow Up Study on Patients with Early Stage Breast Cancer after Breast Conservation Surgery
下载PDF
导出
摘要 目的评价早期乳腺癌患者行保留乳房治疗的疗效。方法选择1990年3月至1993年5月本院乳腺癌患者35例,乳腺癌TNM为Ⅰ期、Ⅱa期行保留乳房手术(BCS)患者,术后行放疗、化疗,受体阳性患者口服三苯氧胺。结果 BCS治疗后优良率为88.6%(31/35)。经18年随访,局部复发4例(11.4%),死亡6例(其中4例死于远处转移,2例死于心血管疾病),总生存率为82.9%(29/35)。结论早期乳腺癌行保留乳房治疗的疗效肯定,不仅生存率等同于同期的改良根治术,而且生活质量明显提高。 Objective To evaluate the long-term effect of breast conservation surgery in early stage patients. Methods 35 patients from March 1990 to May 1993 in our hospital with stage Ⅰ , Ⅱ a breast cancer received conservation surgery combined with post surgery radiation therapy, routine chemical therapy, and hormone therapy. Results In 18 years follow up, local recurrence rate was 11.4%(4/35),overall survival rate was 82.9%(29/35) ,cosmetic satisfaction rate was 88.6%(31/35). Conclusion The patients with early breast cancer benefit from conservation surgery for high survival rate and improved life quality.
出处 《重庆医学》 CAS CSCD 北大核心 2011年第26期2631-2632,共2页 Chongqing medicine
关键词 乳腺肿瘤 保留乳房手术 放射治疗 stage breast neoplasms breast conservation surgery chemotherapy
  • 相关文献

参考文献14

  • 1张保宁.乳腺癌保乳手术的研究进展[J].中国普外基础与临床杂志,2005,12(3):204-206. 被引量:103
  • 2狄根红,吴炅,余科达,陆劲松,沈坤炜,沈镇宙,邵志敏.早期乳腺癌的外科治疗策略[J].中华肿瘤杂志,2007,29(1):62-65. 被引量:16
  • 3Fung MC,Scthulz DJ,Solin LJ.Early-stage bilateral breast cancer treated with breast conserbing surgery and definitive irradiation:the Unibersity of Pennsylvania experience[J].Radiat Oncol Biol Phys,1997,38(5):959.
  • 4Van Tienhoven G,Voogd AC,Peterse JL,et al.Prognosis after treatment for loco-regional after mastectomy or breast conserbing therapy in two randomized trials(EORTC 10801 and DBCG-82TM).CORTC Breast Cancer Cooperative Group and Daimistl Breast Cancer Cooperative Group[J].Eur Jcancer,1995,35(1):32-38.
  • 5Anscher M,Jones P,Prosnitz L,et al.Local failure and marfinstatus in early-stage breast carcinoma treated with conservation surfery and radiation therapy[J].Ann Surg,1993,218(1):22-28.
  • 6Spivak B,Khanna M M,Tafra L,et al.Margin status and local recurrendce after breast-conserving surgery[J].Arch Surg,1994,129(9):952-957.
  • 7Smitt MC,Nowels KW,Zdeblick MJ,et al.The importance of the lumpectomy surgical margin status in long term results of breast conservation[J].Cancer,1995,76(2):259-267.
  • 8Olson TP,Harter J,Munoz A,et al.Frozen section analysis for intraoperative margin assessment during breast-conserving surgery results in low rates of re-excision and local recurrence[J].Ann Surg Oncol,2007,14(10):2953-2960.
  • 9Veronesi U,Cascineli N,Mariani L,et al.Twenty-year follow-up of a randomized study comparing breast-consering surgery withradical mastectomy for early breast cancer[J].N Engl J Med,2002,347(16):1227-1232.
  • 10Fisher B,Anderson S,Bryant J,et al.Twenty-year follow-up of a randomized trial compadng total mastectomy,lumpectomy,and lumpectomy plus irradiation for the treatment of invasiveive breast cancer[J].N Engl J Med,2002,347(16):1233-1241.

二级参考文献17

  • 1狄根红,亓发芝,吴炅,陆劲松,沈坤炜,沈镇宙,邵志敏.乳腺癌改良根治术后一期乳房再造[J].复旦学报(医学版),2004,31(4):434-435. 被引量:35
  • 2张保宁.乳腺癌保乳手术的研究进展[J].中国普外基础与临床杂志,2005,12(3):204-206. 被引量:103
  • 3付丽.从病理角度探讨乳腺癌的保乳疗法[J].中华肿瘤杂志,2005,27(6):383-384. 被引量:17
  • 4Fisher B, Redmond C, Fisher ER, et al. Ten-year results of a randomized clinical trial comparing radical mastectomy and total mastectomy with or without radiation [J]. N Engl J Med, 1985; 312(11):674.
  • 5Fisher B, Anderson S, Redmond CK, et al. Reanalysis and results after 12 years of follow-up in a randomized clinical trial comparing total mastectomy with lumpectomy with or without irradiation in the treatment of breast cancer [J]. N Engl J Med, 1995; 333(22):1456.
  • 6Early Breast Cancer Trialists' Collaborative Group. Effects of radiotherapy and surgery in early breast cancer. An overview of the randomized trials [J]. N Engl J Med, 1995; 333(22):1444.
  • 7Van Lancker M, Goor C, Sacre R, et al. Patterns of axillary lymph node metastasis in breast cancer [J]. Am J Clin Oncol, 1995; 18(3):267.
  • 8Hayman J, Schmitt S, Gelman R, et al. A prospective trial of conservative surgery (CS) alone without radiation therapy (RT) in xelected patients with early-stage breast cancer [J]. Int J Radiot Oncol Biol Phys, 1995; 32(1):209.
  • 9Fisher B, Anderson S, Bryant J, et al. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med, 2002, 347:1233-1241.
  • 10Veronesi U, Cascinelli N, Mariani L, et al. Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer. N Engl J Med, 2002,347 : 1227-1232.

共引文献115

同被引文献24

引证文献4

二级引证文献17

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部