低频超声控释尿激酶缓释系统对大鼠脑出血行为学改善的观察
被引量:1
摘要
本课题组在前期已经研究了pluronic P-105[1]-尿激酶缓释系统在低频超声的控制下缓慢释放,在大鼠脑出血中,其溶解血肿的效果要优于普通尿激酶,当时虽然也进行了行为学的评价及比较.因为样本量较少,其行为学的变化,NP—UK系统虽然较普通尿激酶组有改善,但统计学上无明显差异。为了进一步研究NP—UK系统对脑出血的治疗情况.评价其对行为学的改善情况,我们进行了此研究,现报告如下。
出处
《中国药物与临床》
CAS
2011年第9期1025-1026,共2页
Chinese Remedies & Clinics
基金
上海市科委攻关资助课题(064119646)
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二级参考文献24
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共引文献36
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1王燃,付向,朱炜炜,周宇.脑室内出血灌注尿激酶保留时间探讨[J].现代临床医学,2006,32(4):285-287. 被引量:1
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同被引文献4
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1刘丛,程远,于锐,马颖,刘德华,王志刚.低频超声对猪脑内血肿助溶作用的实验研究[J].中国超声医学杂志,2005,21(2):81-84. 被引量:3
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2赵海滨.赵成波,卢士平,等.低频超声联合微创术治疗脑出血疗效研究.中国全科医学,2009,12(5):377-378.
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3贺宇波,段友容,刘卫东,孙伟,钱忠心,严志忠.低频超声控释尿激酶缓释系统在大鼠脑出血中的应用研究[J].河北医科大学学报,2008,29(6):809-814. 被引量:5
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4郑伟,孙大勇.低频超声联合微创术治疗脑出血疗效研究[J].中国实用医药,2014,9(16):67-68. 被引量:2
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1孙伟,刘卫东,段友容,毛青,亓雪莲,钱忠心,龚良,赵明珠.超声控释对载尿激酶缓释系统助溶的研究[J].临床超声医学杂志,2008,10(1):1-4. 被引量:3
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2孙伟,段友容,刘卫东,亓雪莲,贺宇波,严志忠.超声控释载尿激酶缓释给药系统的体外实验[J].中国新药与临床杂志,2008,27(3):173-176. 被引量:6