摘要
自然界中存在着种类繁多的毒素物质,但最有可能用作战剂的是那些获取方便、制备容易、毒性强、施放后可致人死亡或失能的毒素。毒素战剂既不同于传统的细菌、病毒战剂,也不同于化学毒剂,其最大的威胁来自它的高毒性及缺乏有效的治疗手段。因此,发展毒素战剂的检测识别分子与防治药物就显得尤为重要。本文讨论了生物毒素战剂相关概念、特征,重点综述了毒素战剂的检测识别分子与防治药物研究进展。
There are various types of toxins in nature. However, these toxins, which are characterized by the ready availability, easy production and high toxicity, arc likely bi~）logical warfare agents. Toxin warfare agents are different from traditional bacterial and viral agents or from chemical warfare agents in that they pose a great threat because of their diverse potency and the lack of efficacious drugs. Therefore, it is quite important to develop specific, sensitive recognition mole- cules for detection of toxins and drugs against intoxication caused by toxin agents. This review focuses on advances in recog- nition molecules of toxins and some drugs used as prevention and treatment based on the characteristics of toxin warfare agents
出处
《军事医学》
CAS
CSCD
北大核心
2011年第8期561-565,共5页
Military Medical Sciences
基金
军队“十一五”计划专题项目(06Z069)
关键词
生物毒素
生物战剂
识别分子
治疗药物
疫苗
biological toxins
biological warfare agents
recognition molecules
therapeutic drugs
vaccines
