摘要
天然蒙脱石是一种由膨润土提纯而来的非金属矿物,是一种2∶1型的粘土矿,即两个硅氧四面体亚层中间夹一个铝氧八面体亚层。该单位晶胞结构使其在医药领域的应用中具有独特的优势。蒙脱石作为一种性能良好的药用辅料,可应用于新型药物载体的开发,将有助于设计药物新剂型和寻找适宜的给药途径。本文综述了蒙脱石作为药物载体应用于医药领域的国内外最新研究进展。
Montmorillonite,refined from bentonite,is one type of nonmetallic minerals.It is a 2∶1 day,meaning that it has 2 tetrahedral sheets sandwiching a centrat octahedral sheet.It's the nuique crystal structure that gains an advantage in the applications of medical field.As a fine pharmaceutic excipient,it can be developed as new drug carriers to help design new drug formmlation and search for more suitable administration routes.This article reviews on the research progress of montmorillonite as drug carriers in recent years.
出处
《中国临床药理学与治疗学》
CAS
CSCD
2011年第8期956-960,共5页
Chinese Journal of Clinical Pharmacology and Therapeutics
关键词
蒙脱石
斑脱土
药物载体
药物运输系统
Montmorillonite
Bentonite
Drug carrier
Drug delivery system