摘要
目的对早期预测急性一氧化碳中毒迟发性脑病的相关因素进行评价。方法回顾性研究分析143例急性一氧化碳中毒患者,在患者入院后统计年龄、性别、基础病、并发症、中毒昏迷时间、高压氧治疗时间、恢复期精神刺激、白细胞计数、高敏C反应蛋白9项相关因素,应用Cox比例风险模型检验各因素与急性一氧化碳中毒迟发性脑病的关系。结果基础病、中毒昏迷时间、高压氧治疗时间、恢复期精神刺激和高敏C反应蛋白5个因素对预测急性一氧化碳中毒迟发性脑病的发生有统计学意义,而年龄、性别、并发症、白细胞计数和血清肌酸激酶同工酶(CK-MB)对急性一氧化碳中毒迟发性脑病的预测无统计学意义。结论应用Cox比例风险模型能够分析急性一氧化碳中毒迟发性脑病的独立预测因素,基础病、中毒昏迷时间、高压氧治疗时间、恢复期精神刺激及高敏C反应蛋白是预测急性一氧化碳中毒迟发性脑病的主要因素。
Objective To evaluate the prognostic factors of delayed encephalopathy after acute carbon monoxide poisoning.Methods 143 cases with acute carbon monoxide poisoning were studied and 9 factors such as age,sex,fundamental diseases,complications,intoxication time,HBO treatment in acute stage,recovery of mental stimulation,high sensitivity c-reactive protein and WBC were evaluated by Coxs proportional hazard index analysis to locate the significant factors related to prognosis.Results fundamental diseases,intoxication time,HBO treatment in acute stage,recovery of mental stimulation,high sensitive c-reactive protein are the five main factors.No significant difference was found in prognosis with Age,sex,complications and WBC.Conclusions The prognosis of delayed encephalopathy after acute carbon monoxide poisoning may be analyzed by Cox＇s proportional hazard model.Fundamental diseases,intoxication time,HBO treatment in acute stage,recovery of mental stimulation,high sensitive c-reactive protein are the main factors related to the early prognosis of delayed encephalopathy after acute carbon monoxide poisoning.
出处
《滨州医学院学报》
2011年第4期282-284,共3页
Journal of Binzhou Medical University
关键词
急性一氧化碳中毒
迟发性脑病
预测
COX比例风险模型
acute carbon monoxide poisoning
delayed encephalopathy
prognosis
Cox＇s proportional hazard model
