期刊文献+

MMC在青光眼小梁切除联合白内障囊外摘除术中的应用效果 被引量:1

Effect of mitomycin C in the surgery of trabeculectomy combined with extracapsular cataract extraction
下载PDF
导出
摘要 目的:探讨丝裂霉素C(MMC)在青光眼小梁切除联合白内障囊外摘除人工晶状体植入术中的应用效果。方法:选择32例合并有青光眼的硬核白内障患者,随机分为MMC组及对照组,行小梁切除联合白内障囊外摘除人工晶状体植入术。其中MMC组术中使用0.2g/LMMC3min。比较两组在术后12mo内的并发症、手术效果及术后视力。结果:术后两组发生浅前房的几率无显著性差异。术后12mo时MMC组的功能性滤过泡为对照组的2倍,且有显著性差异。术后12mo,MMC组手术失败显著少于对照组,两组最佳矫正视力无显著性差异,且需行Nd:YAG后囊膜激光截开术的患者比例也无显著性差异。两组在随访期均未发生滤过泡渗漏、恶性青光眼以及眼内炎等并发症。结论:MMC可在一定程度上增加青光眼滤过联合白内障囊外摘除人工晶状体植入三联手术的成功率,且没有增加并发症的发生率。 AIM:To investigate the effect of mitomycin C in the surgery of trabeculectomy combined with extracapsular cataract extraction and IOL implantation.METHODS:Thirty-two patients with glaucoma and cataract were chosen and randomized to two groups,mitomycin group and control group.Both of the two groups were performed trabeculectomy combined with extracapsular cataract extraction and IOL implantation.0.2g/L mitomycin C was used for 3minutes in the mitomycin group.The complications,operative effect and postoperative visual acuity were compared 12 months after surgery.RESULTS:There were no significant differences in shallow anterior chamber,best corrected visual acuity and patients who needed Nd:YAG posterior capsulotomy in two groups,but the incidence of functional filter bleb in mitomycin group was significant more than that of control group,and the failure of the surgery in mitomycin group was significant less than that of control group.Both groups had no bleb leak,malignant glaucoma or endophthalmitis in follow-up.CONCLUSION:Mitomycin C can certainly increase the success of triple surgery without increasing the incidence of complications.
出处 《国际眼科杂志》 CAS 2011年第10期1762-1764,共3页 International Eye Science
关键词 丝裂霉素C 青光眼 滤过手术 白内障 囊外摘除 mitomycin C glaucoma filtration surgery cataract extracapsular cataract extraction
  • 相关文献

参考文献7

  • 1Kahmann L,Beyer U,Mehlhorn G,et al.Mitomycin C in patients with gynecological malignancies.Onkologie 2010;33(10):547-557.
  • 2Wilkins M,Indar A,Wormald R.Intraoperative mitomycin c for glaucoma surgery.Cochrane Database Syst Rev 2005;19(4):CD002897.
  • 3Tham CC,Kwong YY,Leung DY,et al.Phacoemulsification versus combined phacotrabeculectomy in medically controlled chronic angle closure glaucoma with cataract.Ophthalmology 2008;115 (12):2167-2173.
  • 4Tham CC,Kwong YY,Leung DY,et al.Phacoemulsification versus combined phacotrabeculectomy in medically uncontrolled chronic angle closure glaucoma with cataracts.Ophthalmology 2009; 116 (4):725-731.
  • 5董万江,谈刚,刘华,余素英,胡绍柱.青光眼小梁切除术后白内障超声乳化人工晶状体植入术临床分析[J].国际眼科杂志,2011,11(1):126-127. 被引量:12
  • 6Lusthaus JA,Kubay O,Karim R,et al.Primary trabeculectomy with mitomycin C:safety and efficacy at 2 years.Clinical Exp Ophthalmol 2010;38(9):831-838.
  • 7Tous HM,Nevárez J.Comparison of outcomes following combined ECCE-trabeculectomy versus phacoemulsification-trabeculectomy.Puerto Rico Health Sciences Journal 2006;25(4):319-323.

二级参考文献9

共引文献11

同被引文献6

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部