摘要
目的探讨不孕妇女生殖道支原体感染及耐药分析。方法对320例就诊的不孕妇女(不孕组)进行支原体培养和药敏试验,另选择80例同期早孕健康妇女作对照组。结果不孕组妇女的支原体感染率(35.3%)明显高于对照组(12.5%)(χ2=15.64,P<0.01)。支原体对四环素、多西环素以及米诺环素敏感率>65%;对红霉素、阿奇霉素、克拉霉素以及罗红霉素敏感率<50%,对交沙霉素的敏感率为75.2%;对喹诺酮类抗生素诺氟沙星、氧氟沙星、左氧氟沙星以及司帕沙星耐药率均>75%。结论支原体感染,特别UU感染是引起不孕的主要原因之一。四环素类抗生素和交沙霉素可作为本地区支原体治疗的首选药物。
Objective To explore the infection of mycoplasma in genital tracts of sterile woman and the analysis of their drugresistance. Methods Make the cultivation and the susceptibility of the mycoplasma of 320 sterile women （ strile group ）, and 80 healthy women in early pregnancy were choosed as the control group. Results The rate of mycoplasma infection of strile group was significantly higher than that of control group （35.3% vs 12.5%, X^2=15.64, P 〈 0.01 ）. The sensitive rate of mycoplasma to decyeline, doxycycline and minocycline were all 〉 65%, and its rate to erythromyein, azithromycin, clarithromycin and roxithromycin were all 〈 50%, but the rate to josamycin was 75.2%. Its drug-resistant rate to norfloxacin, Ofloxacin, Levofloxacin and sparfloxacin were all 〉 5%. Conclusion The infection of mycoplasma, especially the infection of UU is one of the reasons that cause sterility. The tetracycline antibiotics and josamyein can be the choice drugs in the local area for the mycoplasma.
出处
《中国现代医生》
2011年第28期77-78,共2页
China Modern Doctor
关键词
不孕
支原体
耐药
Sterility
Mycoplasma
Drug-resistance
