摘要
目的:探讨口服铁剂改善孕期贫血及铁储备状态的作用。方法:选择144例妊娠贫血孕妇(贫血组,口服多糖铁复合物胶囊150 mg/次,2次/天)、100例正常孕妇(预防组,口服多糖铁复合物胶囊150 mg/次,1次/天)和50例正常孕妇(对照组,膳食补铁),测定血红蛋白(Hb)、红细胞计数(RBC)、血清铁蛋白(SF)、血清铁(SI)。结果:贫血组和预防组Hb和RBC呈现早-中期下降(P<0.05)、中-晚期上升(P<0.05)的变化,对照组各孕周Hb、RBC呈逐渐下降趋势(P<0.05)。整个孕周3组孕妇SF均呈进行性下降(P<0.01)。3组孕妇SI早-中期下降较为明显(P<0.01)。结论:单纯膳食补铁不能满足孕期对铁的需求。孕期铁储备处于持续消耗状态。需重视孕早期及孕中期铁剂补充。
Objective：To explore the improving effect of oral iron on pregnant women with iron-deficiency anemia（IDA） and iron storage status. Methods：144 pregnant women with IDA（anemia group,treated with oral administration of polysaccharide-iron complex capsules,150 mg per time,twice a day）,100 normal pregnant women（prevention group,treated with oral administration of polysaccharide-iron complex capsules,150 mg per time,once a day） and 50 normal pregnant women（control group,treated with dietary supplementation） were selected.The levels of hemoglobin,red blood cell count,serum ferritin and serum iron were measured. Results：The levels of hemoglobin and red blood cells decreased at early to middle period（P0.05）,then increased at middle to late period in anemia group and prevention group（P0.05）.In control group,the levels of hemoglobin and red blood cells showed a gradual-decreasing trend at different gestational weeks（P0.05）.The level of serum ferritin decreased gradually in the whole gestational age in the three groups（P0.01）.The decrease of serum iron at early to middle period was obvious in the three groups（P0.01）. Conclusion：Simple dietary supplementation can＇t satisfy the iron requirement during pregnancy.Iron storage during pregnancy is in a continuous consumption state,more attention should be paid to iron supplementation during the first and second trimester of pregnancy.
出处
《中国妇幼保健》
CAS
北大核心
2011年第27期4185-4187,共3页
Maternal and Child Health Care of China
关键词
缺铁性贫血
妊娠
Iron deficiency anemia
Pregnancy
