摘要
目的综述苦参碱及其衍生物的最新研究进展。方法通过查阅大量相关文献,对苦参碱及其衍生物的合成和药理活性资料进行整理、分析,并总结了一部分化合物的构效关系。结果与结论大多数苦参碱衍生物在抗肿瘤、抑菌、抗炎镇痛等方面的生物活性都有较大的提高。
OBJECTIVE To introduce advances in research of matrine and its derivates.METHODS Based on the correlative materials from documents,the synthesis and pharmacology of matrine and its derivates had been briefly summarized.The structure-activity relationship of some matrine derivates was included.RESULTS CONCLUSION Many bioactivities of matrine derivates have been improved greatly,such as antitumor,antisepsis,anti-inflammation and analgesicis.
出处
《中国现代应用药学》
CAS
CSCD
北大核心
2011年第9期816-823,共8页
Chinese Journal of Modern Applied Pharmacy
