摘要
目的评价留置导尿术中应用盐酸利多卡因的效果。方法利用计算机检索发表的相关文献,应用Meta分析方法对其进行定量分析评价。结果 12篇文献纳入研究。效应指标疼痛程度存在异质性(P=0.0001<0.05,I2=74%),选用随机效应模型分析,盐酸利多卡因导尿组对降低患者的疼痛感较传统导尿组明显(P<0.01);尿道损伤及插管成功率两项指标不存在异质性,采用固定效应模型分析,盐酸利多卡因导尿组与传统导尿组在降低患者的尿道损伤率和提高插管成率方面的差异具有统计学意义(P<0.01)。结论盐酸利多卡因导尿法较常规导尿法的导尿效果好,但由于检索的数据库较少,有必要查找更多设计严谨的随机对照试验来进一步论证。
Objective To assess the effect of lidocaine hydrochloride in application of indwelling catheterization.Methods Computer retrieval was conducted to search for the relevant published literature,Meta-analysis was used for quantitative aggregate analysis on related articles.Results Only 12 articles were included in the study.Meta analyses showed that the index of pain was general heterogeneity（P=0.000 1 0.05,I2=74%）,analysis was done with random effects model.The result illustrated that the pain in the lidocaine hydrochloride catheterization group was obviously reduced than that of the traditional catheterization group（P 0.01）.Both the index of urethral injury and intubation success rate had no heterogeneity,analysis was done with fixed effects model.The result illustrated that there was significant differenc between the observation group and the control group in decreasing the rate of urethral injury and improving intubation success rate（P 0.01）.Conclusion Lidocaine hydrochloride catheterization methods tended to be superior to traditional methods.However,searchable database of this study was few,it is necessary to find more randomized controlled trials for further proof.
出处
《中国药业》
CAS
2011年第19期8-10,共3页
China Pharmaceuticals
关键词
盐酸利多卡因
留置导尿
META分析
lidocaine hydrochloride
indwelling catheterization
Meta-analysis
