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再生蛋白4与CA-199联合检测在胰腺癌诊断中的临床意义 被引量:1

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摘要 胰腺癌是个预后极差的恶性肿瘤,5年生存率少于4%,早期诊断和早期治疗是1种可行的能有效提高患者5年生存率的方法。但由于胰腺癌解剖位置较深,临床症状缺乏特异性及无有效的筛查方法,大多数患者发现时已属于中晚期。本研究对再生蛋白4(regenerating islet-derived 4,REG4)与CA-199联合检测在早期诊断胰腺癌中的作用进行了初步探讨,现报告如下。
出处 《实用癌症杂志》 2011年第5期510-510,共1页 The Practical Journal of Cancer
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  • 1吴健民.对肿瘤标志物的再认识[J].中华检验医学杂志,2005,28(1):11-13. 被引量:116
  • 2Koprowski H, Herly M, Steplewski Z, et al. Specific in serum of patients with colon carcinoma[J]. Science, 1981,212 : 53.
  • 3Rosty C,Goggins M. Early detection of pancreatic carinoma[J]. Hematol Oncol Clin Am, 2002,16 : 37.
  • 4Hartupee JC,Zhang H,Bonaldo MF,et al.Isolation and characterization of a cDNA encoding a novel member of the human regenerating protein family:Reg Ⅳ[J].Biochim Biophys Acta,2001,1518(3):287-293.
  • 5Watanabe T,Yonekura H,Terazono K,et al.Complete nucleotide sequence of human reg gene and its expression in normal and tumoral tissues.The reg protein,pancreatic stone protein,and pancreatic thread protein are one and the same product of the gene[J].J Biol Chem,1990,265(13):7432-7439.
  • 6Takehara A,Eguchi H,Ohigashi H,et al.Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4[J].Cancer Sci,2006,97(11):1191-1197.
  • 7Takayama R,Nakagawa H,Sawaki K,et al.Serum tumor antigen REG4 as a diagnostic biomarker in pancreatic ductal adenocarcinoma[J].J Gastroenterol,2010,45(1):52-59.
  • 8Zheng HC,Xu XY,Yu M,et al.The role of Reg Ⅳ gene and its encoding product in gastric carcinogenesis[J].Hum Pathol,2010,41(1):59-69.
  • 9Mitani Y,Oue N,Matsumura S,et al.Reg Ⅳ is a serum biomarker for gastric cancer patients and predicts response to 5-fluorouracil-based chemotherapy[J].Oncogene,2007,26(30):4383-4393.
  • 10Oue N,Kuniyasu H,Noguchi T,et al.Serum concentration of Reg Ⅳ in patients with colorectal cancer:,overexpression and high serum levels of Reg Ⅳ are associated with liver metastasis[J].Ontology,2007,72(5-6):371-380.

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