摘要
目的研究肾细胞癌淋巴结转移的危险因素,并建立Logistic回归模型。方法 2000年2月～2008年10月本院手术治疗的肾细胞癌163例,对其临床病理资料进行单因素和多因素的Logistic回归分析。结果淋巴结转移的发生率为20.9%(34/163)。单因素分析显示,肿瘤大小、临床分期、Fuhrman核分级和贫血与肾细胞癌淋巴结转移的风险有关(P<0.05);多因素分析显示,肿瘤大小、临床分期和Fuhrman核分级是RCC淋巴结转移独立的危险因素。结论肾细胞癌淋巴结转移的风险与肿瘤大小、临床分期和Fuhrman核分级有关,Logistic回归模型对于判断预后、指导术后治疗及随访方案的制订具有重要作用。
Objective To study the risk factors of lymph node metastasis of renal cell Carcinoma（RCC） and to set up a Logistic regression model. Methods The clinical data of 163 patients with renal cell carcinoma who underwent radical nephrectomy from July 2000 to July 2008 in Affiliated Tumor Hospital of Xinjiang Medicial University, were analyzed by univariate and binary Logistic regression. Results The incidence of lymph node metastasis was 20. 9%. Univariate logistic analysis revealed that the tumor size, clinical stage, Fuhrman nuclear grade and anemia were all correlated with lymph node metastasis of RCC （ P 〈 0.05 ）. Binary logistic analysis found that the tumor size （ OR = 1. 828, P 〈 0. 01 ）, clinical stage （ OR = 6. 296, P 〈0. 01 ）and the Fuhrman nuclear grade（ OR =0. 377, P 〈0. 05 ）were the independettt risk factors responsible for lymph node metastasis of RCC. Conclusion The risk factors for lymph node metastasis in patients with renal cell carcinoma were correlated with the tumor size ,clinical stage and Fuhrman nuclear grade, The Logistic regression model may be useful for progxmsis and making the postoperative treatment and follow - up program for patients with RCC.
出处
《中国医学创新》
CAS
2011年第28期13-15,共3页
Medical Innovation of China
关键词
肾肿瘤
淋巴结转移
危险因素
回归分析
Renal cell carcinoma
Lymph node metastasis
Risk factors
Regression analysis
